Results 41 to 50 of about 9,519 (266)

On Inconsistent Bayes Estimates of Location

open access: yesThe Annals of Statistics, 1986
This paper is related to the authors paper ibid. 14, 1-26 (1986; see the foregoing review, Zbl 0595.62022). In some relatively natural settings, Bayes estimates of location are shown to be inconsistent.
Diaconis, P., Freedman, D.
openaire   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Bayesian Estimation of the Reliability Function of a Two-parameter Cauchy Distribution. [PDF]

open access: yesThe Egyptian Statistical Journal, 1998
            In this paper, we obtained an approximate Bayes procedure for the estimation of the reliability function of a two-parameter Cauchy distribution under a predictive distribution approach of Sinha and Guttman (1988) using Jeffrys' non ...
T. Abdel Moneim
doaj   +1 more source

On Bayes estimates

open access: yesJournal of Multivariate Analysis, 1973
AbstractIn this paper the author tries to give general conditions for the existence of Bayes estimates and for the consistency of sequences of Bayes estimates.In Section 3 we prove existence theorems for Bayes estimates, which contain those of DeGroot and Rao [3], as a special case.
openaire   +2 more sources

Bayes Estimation with Convex Loss

open access: yesThe Annals of Mathematical Statistics, 1963
Let $X$ be a generalized random variable taking values in an abstract set $\mathscr{X}$ on which is defined an appropriate $\sigma$-field of subsets. Suppose that the distribution of $X$ depends on a real parameter $\Theta$ and that it is desired to estimate the value of $\Theta$ from an observation on $X$.
DeGroot, M. H., Rao, M. M.
openaire   +2 more sources

A Bayes Linear Bayes Method for Estimation of Correlated Event Rates [PDF]

open access: yesRisk Analysis, 2013
Typically, full Bayesian estimation of correlated event rates can be computationally challenging since estimators are intractable. When estimation of event rates represents one activity within a larger modeling process, there is an incentive to develop more efficient inference than provided by a full Bayesian model.
Quigley, John   +3 more
openaire   +4 more sources

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Bayes Shrinkage Estimation of the Parameter of Rayleigh Distribution for Progressive Type-II Censored Data

open access: yesAustrian Journal of Statistics, 2015
This paper derives Bayes shrinkage estimator of Rayleigh parameter and its associated risk based on conjugate prior under the assumption of general entropy loss function for progressive type-II censored data. Risk function of maximum likelihood estimate,
Sanku Dey   +2 more
doaj   +1 more source

On a Stress-Strength Model in Weibull Case [PDF]

open access: yesThe Egyptian Statistical Journal, 1996
In this paper three estimators for the reliability function P (Y < X), (MLE, UMVUE and Bayes estimators) are given when X and Y are two independent but not identically distributed Weibull random variables with common and known shape parameter.
M. Mahmoud
doaj   +1 more source

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