Results 31 to 40 of about 907,345 (263)

Comparative Enumeration Gene Expression [PDF]

open access: yes, 2008
This paper is about differential gene expression measured by transcript counting methods such as SAGE or MPSS. It introduces two significance tests for detection of differential expressed tags: frequentist and Bayesian. Under the frequentist view, it is
Carlos A. D. E. B. Pereira   +1 more
core   +2 more sources

Optimization of non-periodic inspection of structural components by Bayesian approach

open access: yesMechanical Engineering Journal, 2018
This paper presents an advanced Bayesian analysis method to determine the appropriate non-periodic inspection intervals of fatigue-sensitive structures. The calculation procedure of the posterior distribution is improved compared to the previous methods.
Haoyu HUANG   +3 more
doaj   +1 more source

Computational methods for Bayesian model choice

open access: yes, 2009
In this note, we shortly survey some recent approaches on the approximation of the Bayes factor used in Bayesian hypothesis testing and in Bayesian model choice.
C. P. Robert   +3 more
core   +4 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Bayesian Policy Gradients via Alpha Divergence Dropout Inference

open access: yes, 2011
Policy gradient methods have had great success in solving continuous control tasks, yet the stochastic nature of such problems makes deterministic value estimation difficult.
Henderson, Peter   +3 more
core   +3 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Bayesian Proxy Modelling for Estimating Black Carbon Concentrations using White-Box and Black-Box Models

open access: yesApplied Sciences, 2019
Black carbon (BC) is an important component of particulate matter (PM) in urban environments. BC is typically emitted from gas and diesel engines, coal-fired power plants, and other sources that burn fossil fuel.
Martha A. Zaidan   +3 more
doaj   +1 more source

Linear Bayesian Methods

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1969
Summary A method of linear prediction is proposed, which follows the Bayesian scheme in combining prior and present information, but which uses only the first two moments of the distribution of parameters and observations, rather than the complete probability model required of Bayesian techniques.
openaire   +2 more sources

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Evaluation of genome-enabled selection for bacterial cold water disease resistance using progeny performance data in rainbow trout: Insights on genotyping methods and genomic prediction models

open access: yesFrontiers in Genetics, 2016
Bacterial cold water disease (BCWD) causes significant economic losses in salmonid aquaculture, and traditional family-based breeding programs aimed at improving BCWD resistance have been limited to exploiting only between-family variation.
Roger L. Vallejo   +8 more
doaj   +1 more source

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