Results 51 to 60 of about 907,345 (263)

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

Bayesian and Non-Bayesian Estimation Methods for Simulating the Parameter of the Akshaya Distribution

Computational Journal of Mathematical and Statistical Sciences, 2022
The ”Akshaya distribution” is a model one-parameter continuous distribution that has been proposed by [15] for modelling lifetime data from biological research and engineering.
Ahlam. H. Tolba
doaj   +1 more source

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

Arthritis Care &Research, EarlyView.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello, Rui Xiao, Xuemei Zhang, Jahan Jazayeri, Irit R. Rasooly, Pamela F. Weiss   +5 more
wiley   +1 more source

An independent assessment of significance of annual modulation in COSINE-100 data

The Open Journal of Astrophysics, 2019
We perform an independent search for annual modulation caused by dark matter-induced scatterings in the recently released COSINE-100 data. We test the hypothesis that the data contains a sinusoidal modulation against the null hypothesis that the ...
Aditi Krishak, Shantanu Desai
doaj   +1 more source

Trajectories of Physical Function in Canadian Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objectives We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham, Meghan McPherson, Lillian Lim, Roberta A. Berard, Matthew Berkowitz, Jean‐Philippe Proulx‐Gauthier, Brian M. Feldman, Nicole Johnson, Dax G. Rumsey, Heinrike Schmeling, Lori B. Tucker, Thomas Loughin, Kristin M. Houghton, Jaime Guzman, The CAPRI Registry Investigators   +14 more
wiley   +1 more source

A DSGE Model for the Slovenian Economy: Model Estimates and Application

Economic and Business Review, 2019
The paper presents the estimation of a dynamic stochastic general equilibrium (DSGE) model for the Slovenian economy and its applications. The model, which is built in the tradition of New Keynesian models, closely follows the structure of the model ...
Andrej Kuštrin
doaj   +1 more source

Biopsychosocial determinants of hand function and its trajectories over five years in patients with hand osteoarthritis

Arthritis Care &Research, Accepted Article.
Objectives This study aimed to investigate hand function trajectories over 5 years in primary hand osteoarthritis. Additionally, determinants of baseline and longitudinal hand function were assessed. Methods 538 patients with both baseline and 5‐year study visits were analyzed.
Annemiek V.E.M. Olde Meule, Coen van der Meulen, Jos Runhaar, Frits R. Rosendaal, Margreet Kloppenburg   +4 more
wiley   +1 more source

Coach Turnover in Top Professional Brazilian Football Championship: A Multilevel Survival Analysis

Frontiers in Psychology, 2019
In this study, we examined the probability of coaches’ survival in the top Brazilian professional football championship considering variation across the competitive seasons between 2012 and 2017, considering a multilevel framework.
Alexandre B. Tozetto, Alexandre B. Tozetto, Humberto M. Carvalho, Rodolfo S. Rosa, Felipe G. Mendes, Walan R. Silva, Juarez V. Nascimento, Michel Milistetd   +7 more
doaj   +1 more source

High-Order Stochastic Gradient Thermostats for Bayesian Learning of Deep Models

, 2015
Learning in deep models using Bayesian methods has generated significant attention recently. This is largely because of the feasibility of modern Bayesian methods to yield scalable learning and inference, while maintaining a measure of uncertainty in the
Carin, Lawrence, Chen, Changyou, Fan, Kai, Li, Chunyuan   +3 more
core   +1 more source

Obesity subtypes and longitudinal trajectories of function over 7‐years of follow‐up: data from the Multicenter Osteoarthritis Study

Arthritis Care &Research, Accepted Article.
Background Obesity, defined by BMI ≥30kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA.
Kristine Godziuk, Sarah Tilley, Michael LaValley, Michael C. Nevitt, Cora E. Lewis, James C. Torner, Tuhina Neogi   +6 more
wiley   +1 more source