Results 231 to 240 of about 6,917,983 (390)

A prospective, phase II, neoadjuvant study based on chemotherapy sensitivity in HR+/HER2‐ breast cancer‐FINEST study

open access: yesCancer Communications, EarlyView.
Abstract Background Hormone receptor‐positive (HR+)/humaal growth factor receptor 2‐negative (HER2‐) breast cancer, the most common breast cancer type, has variable prognosis and high recurrence risk. Neoadjuvant therapy is recommended for median‐high risk HR+/HER2‐ patients.
Li Chen   +10 more
wiley   +1 more source

Network meta‐analysis of randomized trials in multiple myeloma: Efficacy and safety in frontline therapy for patients not eligible for transplant

open access: yesHematological Oncology, Volume 40, Issue 5, Page 987-998, December 2022., 2022
Abstract The treatment scenario for newly‐diagnosed transplant‐ineligible multiple myeloma patients (NEMM) is quickly evolving. Currently, combinations of proteasome inhibitors and/or immunomodulatory drugs +/− the monoclonal antibody Daratumumab are used for first‐line treatment, even if head‐to‐head comparisons are lacking.
Cirino Botta   +17 more
wiley   +1 more source

Pan‐cancer analysis shapes the understanding of cancer biology and medicine

open access: yesCancer Communications, EarlyView.
Abstract Advances in multi‐omics datasets and analytical methods have revolutionized cancer research, offering a comprehensive, pan‐cancer perspective. Pan‐cancer studies identify shared mechanisms and unique traits across different cancer types, which are reshaping diagnostic and treatment strategies.
Xiaoping Cen   +21 more
wiley   +1 more source

SPiP: Splicing Prediction Pipeline, a machine learning tool for massive detection of exonic and intronic variant effects on mRNA splicing

open access: yesHuman Mutation, Volume 43, Issue 12, Page 2308-2323, December 2022., 2022
Abstract Modeling splicing is essential for tackling the challenge of variant interpretation as each nucleotide variation can be pathogenic by affecting pre‐mRNA splicing via disruption/creation of splicing motifs such as 5′/3′ splice sites, branch sites, or splicing regulatory elements.
Raphaël Leman   +35 more
wiley   +1 more source

Digital Metallo‐Supramolecular Chemistry

open access: yesChemistryEurope, EarlyView.
Self‐driving laboratories powered by mobile robotics and heuristic algorithms are transforming the landscape of metallo‐supramolecular chemistry. This work highlights an integrated system for automating the synthesis and characterisation of metal–organic cages (MOCs), enabling rapid exploration of complex chemical spaces.
Aleksandar Kondinski
wiley   +1 more source

Integrative Bayesian Network Analysis of Genomic Data

open access: yesCancer Informatics, 2014
Yang Ni   +2 more
doaj  

Home - About - Disclaimer - Privacy