Results 101 to 110 of about 942,691 (276)

Model‐Informed Approaches for Pediatric Type 2 Diabetes Evidence Generation: Insights from a Model‐Based Longitudinal HbA1c Meta‐Analysis from EMA Marketing Authorization Applications

Clinical Pharmacology &Therapeutics, EarlyView.
Evidence generation for antihyperglycemic therapies in pediatric type 2 diabetes mellitus (T2DM) remains challenging, with most randomized trials failing to demonstrate statistically significant reductions in glycated hemoglobin (HbA1c), partly due to substantial between‐subject variability.
Pieter J. Colin, Efthymios Manolis, Jeroen V. Koomen   +2 more
wiley   +1 more source

Calibration Procedures for Approximate Bayesian Credible Sets

, 2019
We develop and apply two calibration procedures for checking the coverage of approximate Bayesian credible sets, including intervals estimated using Monte Carlo methods.
Nicholls, GK, Ryder, RJ, Lee, Jeong
core  

Evaluating Vaginal Microbiome Effects on Antiretroviral Exposure in the Female Genital Tract Using Pharmacometric and Machine Learning Approaches

Clinical Pharmacology &Therapeutics, EarlyView.
Antiretroviral pre‐exposure prophylaxis (PrEP) is less effective in women than expected, partly because drug exposure within the female genital tract is variable and may be influenced by the vaginal microbiome. We developed an integrated pharmacometrics and machine learning framework to evaluate associations between vaginal microbiome composition and ...
Diqin Yan, Lindsey B. Collins, Christopher Staley, Flavia Kiweewa Matovu, Pamala Jacobson, Melanie Nicol, Shen Cheng   +6 more
wiley   +1 more source

Does Internal Corporate Social Responsibility Drive Employee Well‐Being? Evidence From a Positive Balance Perspective

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The significance of fostering an internal corporate social responsibility (ICSR) plan to advance employee well‐being is not fully understood. This article explores employee well‐being from a positive balance perspective, combining the strategic approach to Internal Corporate Social Responsibility with the Theory of subjective well‐being ...
Teresa C. Herrador‐Alcaide, João Correia Leitão, Montserrat Hernández‐Solís, Dina Pereira   +3 more
wiley   +1 more source

The AI Sustainability Paradox: How Verification and Regulation Synergize to Curb Greenwashing in Emerging Markets

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Artificial intelligence (AI) reflects a paradox for corporate sustainability: it provides tools for genuine socio‐economic improvement and enables greenwashing at scale. This study examines this duality in emerging Asian markets, where rapid AI adoption coincides with evolving regulatory regimes.
Ashutosh Yadav, Simplice A. Asongu
wiley   +1 more source

Evaluation of fall‐seeded cover crops for grassland nesting waterfowl in eastern South Dakota

Wildlife Society Bulletin, EarlyView., 2023
Cover crops are experiencing a revival among Midwestern farmers, and we assessed their attractiveness and safety for nesting ducks in South Dakota. Nest success was markedly lower in cover crops than in perennial cover during both years of our study, including 2019 which was a best‐case scenario for cover crops, with extremely wet conditions delaying ...
Charles W. Gallman, Todd W. Arnold, Eric S. Michel, Joshua D. Stafford   +3 more
wiley   +1 more source

Environment Friendly Sustainable End‐Of‐Life Solutions for Plastic Components in Indian Automotive Industries

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Growing concerns about the environmental and social consequences of plastics around the world, manufacturing industries are associated with business are focusing on sustainable end‐of‐life options‐based solutions which aim at increasing the product life cycle.
Sivakumar Kirupanandan, Deepak Mathivathanan, Jayakrishna Kandasamy, Michele Mosca   +3 more
wiley   +1 more source

Human pressure, habitat heterogeneity and species traits jointly determine the level of dark diversity in coastal fish communities

Ecography, EarlyView.
Understanding how anthropogenic pressures and environmental gradients shape coastal fish communities is a central question in biogeography and marine conservation. Yet, the set of species expected to occur at a site given ecological conditions but being absent – the so‐called dark diversity – has received far less attention than observed species, even ...
Loïc Sanchez, Jeanne Rolland, Adèle Barroil, Célia Bertrand, Agathe Blandin, Pierre Boissery, Thomas Bockel, Eric Charbonnel, Julie Deter, Régis Hocdé, Florian Holon, Jean‐Baptiste Juhel, Nicolas Loiseau, Bastien Macé, Anthony Maire, Stéphanie Manel, Marie Orblin, Franck Pichot, Jean‐Jacques Riutort, Lola Romant, Rémy Simide, Alice Valentini, Laure Velez, David Mouillot   +23 more
wiley   +1 more source

Euromaidan and Ukrainian Subjective Well‐Being

European Journal of Social Psychology, EarlyView.
ABSTRACT The 2013–2014 Euromaidan in Ukraine was the largest series of pro‐European protests in history. Peaceful civilian protests were met with state violence, resulting in widespread civil unrest, over 100 deaths, and nearly 2000 injuries. The Russo‐Ukrainian War broke out shortly after. We examined the immediate and long‐term changes in Ukrainians’
Aidan Campbell, Elizabeth W. Chan, Kenith Chan, Daniel J. Chiacchia, Ashley K. Dhillon, McLean Morgan, Evi Myftaraj, Haeyoung Gideon Park, Vadym Vasiutynskyi, Felix Cheung   +9 more
wiley   +1 more source

The effect of antiseizure medications on the exposure to combined oral contraceptives: A systematic review and network meta‐analysis

Epileptic Disorders, EarlyView.
Abstract Objective Current recommendations for prescribing combined oral contraceptives (COCs) to people with epilepsy are often conflicting, particularly for weak inducers of cytochrome P450 3A4. We aimed to critically review the literature and compare the antiseizure medication (ASM)‐induced changes in exposure to COC components.
Hagar Cohen, Amnah Omar Mahajna, Tomer Ben‐Shushan, Ilan Matok, Sara Eyal   +4 more
wiley   +1 more source