Results 41 to 50 of about 1,626 (283)

Bayesian and non-bayesian evidential updating

open access: yesArtificial Intelligence, 1987
Orthodox probability theory supposes that (1) we commence with known statistical distributions, (2) these distributions give rise to real- valued probabilities, and (3) these probabilities can be updated by the use of Bayes' theorem. Each of these suppositions has been challenged by recent work in computer science concerning the representation and ...
openaire   +2 more sources

Justifying Bayesianism [PDF]

open access: yes, 2013
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Linguistics and Philosophy, 2013.Cataloged from PDF version of thesis.Includes bibliographical references (pages 97-100).Bayesianism, in its traditional form, consists of two claims about ...
Carr, Jennifer Rose
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Bayesian game theorists and non-Bayesian players [PDF]

open access: yesThe European Journal of the History of Economic Thought, 2018
Bayesian game theorists claim to represent players as Bayes rational agents, maximising their expected utility given their beliefs about the choices of other players. I argue that this narrative is inconsistent with the formal structure of Bayesian game theory.
openaire   +3 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

The Possibility of Coherentism and the Stringency of Ceteris Paribus Conditions

open access: yesTheoria, 2015
Schupbach (2008) puts forward a "possibility result" for Bayesian Coherentism, showing that there exist plausible sets of ceteris paribus conditions that imply that coherence is truth-conducive.
Jonah N. Schupbach
doaj   +1 more source

Bayesianism (Recent Uses Of)

open access: yes, 2020
Bayesianism, named after Thomas Bayes (1702 1761), is a family of related approaches in epistemology, philosophy of mind, Decision Theory, and statistics.
Hajek, Alan, Cusbert, John
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

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