Results 131 to 140 of about 636,797 (344)
Advanced Science, EarlyView.Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck +8 more
wiley +1 more source
A new bound for the smallest $x$ with $\pi(x) > li(x)$
, 2009 We reduce the leading term in Lehman's theorem. This improved estimate allows us to refine the main theorem of Bays and Hudson. Entering $2,000,000$ Riemann zeros, we prove that there exists $x$ in the interval $[exp(727.951858), exp(727.952178)]$ for ...
Chao, Kuok Fai, Plymen, Roger
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New concepts in deployable beam structures [PDF]
, 1985 The design of deployable structures involves a complicated tradeoff of packaging efficiency, the overall mechanism associated with deploying and latching beam joints, and the requirements and complexity of the beam deployer/repacker.
Rhodes, M. D.
core +1 more source
Advanced Science, EarlyView.Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider +20 more
wiley +1 more source
Ecotoxicology and Environmental SafetyFreshwater lakes are increasingly subject to simultaneous nutrient enrichment and antibiotic pollution, yet the joint effects of these stressors on microbial network structure remain poorly characterized.
M.D.K. Lakmali Gunathilaka +6 more
doaj +1 more source
Advanced Science, EarlyView.A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu +6 more
wiley +1 more source
A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells
Advanced Science, EarlyView.An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet +5 more
wiley +1 more source
Advanced Science, EarlyView.An Automated ex vivo culture system BaSIC, tailored for SCN slices and cell culture, which automates medium exchange and ensures a stable internal environment is developed. BaSIC enables real‐time observation of tissue/cell responses to diverse but programmed stimuli.
Kui Han +7 more
wiley +1 more source
Selectivity of gillnets in the California Pacific herring roe fishery [PDF]
, 1977 Pacific herring, Clupea harengus, landings were sampled during the 1976 season in San Francisco, Tomales and Outer Bodega bays. Fish were sampled according to the type of gear used to catch them - - roundhaul nets (purse seines and lamparas), beach ...
Dahlstrom, Walter A.
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