Results 51 to 60 of about 130 (105)
Genetic Loci Associated With Periodontitis: The FinnGen Study Based on National Health Registers
Journal of Clinical Periodontology, Volume 52, Issue 9, Page 1263-1275, September 2025.ABSTRACT Aim
To perform a genome‐wide association study (GWAS) for periodontitis in the FinnGen cohort, as genetic factors contribute to periodontitis. Materials and Methods
We included nearly 250,000 Finnish individuals who had visited a dentist in the public healthcare sector for a clinical oral examination. We designed three periodontitis phenotypes Aino Salminen, Kati Hyvärinen, Jarmo Ritari, Ana Caetano, Oleg Kambur, Päivi Mäntylä, Mustafa Yilmaz, Juha Sinisalo, FinnGen, Aarno Palotie, Mark Daly, Bridget Riley‐Gills, Howard Jacob, Dirk Paul, Slavé Petrovski, Heiko Runz, Sally John, George Okafo, Robert Plenge, Joseph Maranville, Mark McCarthy, Margaret G. Ehm, Kirsi Auro, Simonne Longerich, Anders Mälarstig, Katherine Klinger, Clement Chatelain, Matthias Gossel, Karol Estrada, Robert Graham, Dawn Waterworth, Chris O’Donnell, Nicole Renaud, Tomi P. Mäkelä, Jaakko Kaprio, Petri Virolainen, Antti Hakanen, Terhi Kilpi, Jukka Partanen, Anne Pitkäranta, Taneli Raivio, Jani Tikkanen, Raisa Serpi, Tarja Laitinen, Veli‐Matti Kosma, Jari Laukkanen, Marco Hautalahti, Outi Tuovila, Raimo Pakkanen, Jeffrey Waring, Fedik Rahimov, Ioanna Tachmazidou, Chia‐Yen Chen, Zhihao Ding, Marc Jung, Hanati Tuoken, Shameek Biswas, Rion Pendergrass, David Pulford, Neha Raghavan, Adriana Huertas‐Vazquez, Jae‐Hoon Sul, Anders Mälarstig, Xinli Hu, Åsa Hedman, Robert Graham, Manuel Rivas, Ma’en Obeidat, Jonathan Chung, Jonas Zierer, Mari Niemi, Samuli Ripatti, Johanna Schleutker, Mikko Arvas, Olli Carpén, Reetta Hinttala, Johannes Kettunen, Arto Mannermaa, Katriina Aalto‐Setälä, Mika Kähönen, Johanna Mäkelä, Reetta Kälviäinen, Valtteri Julkunen, Hilkka Soininen, Anne Remes, Mikko Hiltunen, Jukka Peltola, Minna Raivio, Pentti Tienari, Juha Rinne, Roosa Kallionpää, Juulia Partanen, Adam Ziemann, Nizar Smaoui, Anne Lehtonen, Susan Eaton, Sanni Lahdenperä, Edmond Teng, Fanli Xu, Laura Addis, John Eicher, Qingqin S. Li, Karen He, Ekaterina Khramtsova, Martti Färkkilä, Jukka Koskela, Sampsa Pikkarainen, Airi Jussila, Katri Kaukinen, Timo Blomster, Mikko Kiviniemi, Markku Voutilainen, Tim Lu, Natalie Bowers, Linda McCarthy, Amy Hart, Meijian Guan, Jason Miller, Kirsi Kalpala, Melissa Miller, Kari Eklund, Antti Palomäki, Pia Isomäki, Laura Pirilä, Oili Kaipiainen‐Seppänen, Johanna Huhtakangas, Nina Mars, Apinya Lertratanakul, Coralie Viollet, Marla Hochfeld, Jorge Esparza Gordillo, Fabiana Farias, Nan Bing, Margit Pelkonen, Paula Kauppi, Hannu Kankaanranta, Terttu Harju, Riitta Lahesmaa, Hubert Chen, Natalie Bowers, Joanna Betts, Rajashree Mishra, Majd Mouded, Debby Ngo, Teemu Niiranen, Felix Vaura, Veikko Salomaa, Kaj Metsärinne, Jenni Aittokallio, Jussi Hernesniemi, Daniel Gordin, Marja‐Riitta Taskinen, Tiinamaija Tuomi, Timo Hiltunen, Amanda Elliott, Mary Pat Reeve, Sanni Ruotsalainen, Audrey Chu, Dermot Reilly, Mike Mendelson, Jaakko Parkkinen, Tuomo Meretoja, Heikki Joensuu, Johanna Mattson, Eveliina Salminen, Annika Auranen, Peeter Karihtala, Päivi Auvinen, Klaus Elenius, Esa Pitkänen, Relja Popovic, Margarete Fabre, Jennifer Schutzman, Diptee Kulkarni, Alessandro Porello, Andrey Loboda, Heli Lehtonen, Stefan McDonough, Sauli Vuoti, Kai Kaarniranta, Joni A. Turunen, Terhi Ollila, Hannu Uusitalo, Juha Karjalainen, Mengzhen Liu, Stephanie Loomis, Erich Strauss, Hao Chen, Rion Pendergrass, Kaisa Tasanen, Laura Huilaja, Katariina Hannula‐Jouppi, Teea Salmi, Sirkku Peltonen, Leena Koulu, David Choy, Ying Wu, Tuula Salo, David Rice, Pekka Nieminen, Ulla Palotie, Maria Siponen, Liisa Suominen, Vuokko Anttonen, Kirsi Sipilä, Hannele Laivuori, Venla Kurra, Laura Kotaniemi‐Talonen, Oskari Heikinheimo, Ilkka Kalliala, Lauri Aaltonen, Varpu Jokimaa, Marja Vääräsmäki, Outi Uimari, Laure Morin‐Papunen, Maarit Niinimäki, Terhi Piltonen, Katja Kivinen, Elisabeth Widen, Taru Tukiainen, Niko Välimäki, Eija Laakkonen, Jaakko Tyrmi, Heidi Silven, Eeva Sliz, Riikka Arffman, Susanna Savukoski, Triin Laisk, Natalia Pujol, Janet Kumar, Iiris Hovatta, Erkki Isometsä, Hanna Ollila, Jaana Suvisaari, Antti Mäkitie, Argyro Bizaki‐Vallaskangas, Sanna Toppila‐Salmi, Tytti Willberg, Elmo Saarentaus, Antti Aarnisalo, Elisa Rahikkala, Kristiina Aittomäki, Fredrik Åberg, Mitja Kurki, Juha Mehtonen, Priit Palta, Shabbeer Hassan, Pietro Della Briotta Parolo, Wei Zhou, Mutaamba Maasha, Susanna Lemmelä, Aoxing Liu, Arto Lehisto, Andrea Ganna, Vincent Llorens, Henrike Heyne, Joel Rämö, Rodos Rodosthenous, Satu Strausz, Tuula Palotie, Kimmo Palin, Javier Garcia‐Tabuenca, Harri Siirtola, Tuomo Kiiskinen, Jiwoo Lee, Kristin Tsuo, Kati Kristiansson, Kati Hyvärinen, Jarmo Ritari, Katri Pylkäs, Minna Karjalainen, Tuomo Mantere, Eeva Kangasniemi, Sami Heikkinen, Nina Pitkänen, Samuel Lessard, Lila Kallio, Tiina Wahlfors, Eero Punkka, Sanna Siltanen, Teijo Kuopio, Anu Jalanko, Huei‐Yi Shen, Risto Kajanne, Mervi Aavikko, Helen Cooper, Denise Öller, Rasko Leinonen, Henna Palin, Malla‐Maria Linna, Masahiro Kanai, Zhili Zheng, L. Elisa Lahtela, Mari Kaunisto, Elina Kilpeläinen, Timo P. Sipilä, Oluwaseun Alexander Dada, Awaisa Ghazal, Anastasia Kytölä, Rigbe Weldatsadik, Anu Loukola, Päivi Laiho, Tuuli Sistonen, Essi Kaiharju, Markku Laukkanen, Elina Järvensivu, Sini Lähteenmäki, Lotta Männikkö, Regis Wong, Auli Toivola, Minna Brunfeldt, Hannele Mattsson, Sami Koskelainen, Tero Hiekkalinna, Teemu Paajanen, Shuang Luo, Shanmukha Sampath Padmanabhuni, Marianna Niemi, Mika Helminen, Tiina Luukkaala, Iida Vähätalo, Jyrki Tammerluoto, Sarah Smith, Tom Southerington, Petri Lehto, Markus Perola, Aki Havulinna, Luigi Nibali, Ulvi Kahraman Gürsoy, Pirkko J. Pussinen +329 morewiley +1 more sourceA comprehensive European Colorectal Cancer Cohort dataset
Scientific DataColorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. The Biobanking and Biomolecular Resources European Research Infrastructure (BBMRI-ERIC) established a CRC-Cohort with European coverage contributed by 26 biobanks from 12 ...Petr Holub, Outi Törnwall, Eva Garcia Alvarez, Rumyana Proynova, Florian Stampe, Saher Maqsood, Maxmilian Ataian, Irene Schlünder, Olli Carpén, Gerrit Meijer, Rudolf Nenutil, Dalibor Valík, Barbara Parodi, Annemieke Hiemstra, Mariska Bierkens, Esmeralda Castanos-Vélez, Frank Ückert, Diogo Alexandre, Ondřej Vojtíšek, Anna-Liisa Bader, Birgit Simell, Caitlin Ahern, Vitomir Horvat, Erik Steinfelder, Matteo Gnocchi, Marco Moscatelli, Alexander Fürbaß, Jiří Horák, Francesca Frexia, Cecilia Mascia, Alessandro Sulis, Giovanni Delussu, Mauro Del Rio, Vittorio Meloni, Luca Pireddu, Simone Leo, Marco Enrico Piras, Martin Kačenga, Stéphanie Gofflot, Sebastian Mate, Hans-Ulrich Prokosch, Paolo Romano, Daniela Pistillo, Michael Hoffmeister, Alexander Brobeil, Amila Kugic, Berthold Huppertz, Valentina Paleari, Heimo Müller, Robert Reihs, Timo Gemoll, Yannick Bantel, Tobias Sjöblom, Kyriacos Kyriacou, Simona di Martino, Gennaro Ciliberto, Ann-Kristin Kock-Schoppenhauer, Martina Oberländer, Jens K. Habermann, Gabriele Husmann, Per-Henrik D. Edqvist, Inti Zlobec, Martin D. Berger, Lars Boeckmann, Fabienne George, Tom Southerington, Daniel P. Brucker, Laurence Faugeras, Joanna Vella, Alex Felice, Malcolm Pace, Chiara Fallerini, Alessandra Renieri, Andreas Hadjisavvas, Karine Sargsyan, Maria A. Loizidou, Tatiana Besse-Hammer, Franziska Vogl, Jan-Eric Litton, Michael Hummel, Kurt Zatloukal, Marialuisa Lavitrano +81 moredoaj +1 more sourceTranscriptomic and Metabolomic Analyses in Monozygotic and Dizygotic Twins
American Journal of Medical Genetics Part A, Volume 197, Issue 4, April 2025.ABSTRACT
Monozygotic (MZ) and dizygotic (DZ) twins are studied to understand genetic and environmental influences on complex traits, however the mechanisms behind twinning are not completely understood. (Epi)genomic studies identified SNPs associated with DZ twinning and DNA methylation sites with MZ twinning.Nikki Hubers, Gabin Drouard, Rick Jansen, René Pool, Jouke Jan Hottenga, Miina Ollikainen, Xiaoling Wang, Gonneke Willemsen, Jaakko Kaprio, Dorret I. Boomsma, Jenny van Dongen +10 morewiley +1 more sourceBBMRI-ERIC Directory data structure changes : Proposal for Change
, 2022 In this document we propose a couple of changes to the data model of the BBMRI-ERIC Directory. Most of these changes are structural changes to make it easier for the National Nodes to fill in the data in the Directory and limit duplication. We also propose the deletion of six fields that were not shown in the User Interface. Four of these fields relate Hodselmans,Aneas, van Enckevort,Estheropenaire +1 more sourceEthical, legal, and social implications in research biobanking: A checklist for navigating complexity
Developing World Bioethics, Volume 24, Issue 3, Page 139-150, September 2024.Abstract
Biobanks’ activity is based not only on securing the technology of collecting and storing human biospecimen, but also on preparing formal documentation that will enable its safe use for scientific research. In that context, the issue of informed consent, the reporting of incidental findings and the use of Transfer Agreements remain a vast ...Olga Tzortzatou‐Nanopoulou, Kaya Akyüz, Melanie Goisauf, Łukasz Kozera, Signe Mežinska, Michaela Th. Mayrhofer, Santa Slokenberga, Jane Reichel, Talishiea Croxton, Alexandra Ziaka, Marina Makri +10 morewiley +1 more sourceAn ethics framework for the transition to an operational learning healthcare system
Learning Health Systems, Volume 8, Issue 3, July 2024.Abstract Introduction
While Learning Healthcare Systems (LHSs) have received increasing attention in health care and research, the amount of operational LHSs remains limited. Given the investment of resources in these projects, a moral responsibility to pursue the transition toward an LHS falls on projects and their participating stakeholders.Marieke J Hollestelle, Rieke van der Graaf, Miriam CJM Sturkenboom, Johannes JM van Delden +3 morewiley +1 more sourceAbstracts
Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).wiley +2 more sourcesBiobanks in cardiovascular disease research
Кардиоваскулярная терапия и профилактикаA systematic review of publications from the PubMed and eLibrary. ru databases, Biobanking and Biomolecular Resources Research Infrastructure — European Research Infrastructure Consortium (BBMRI-ERIC) and ClinicalTrials.gov studies was carried out for 15 A. M. Gusakova, E. S. Kravchenko, T. E. Suslova, S. V. Popov, A. A. Boshchenko +4 moredoaj +1 more sourceImplementation of the BBMRI-ERIC architecture and database
, 2016 Alexandre, Diogo, Lablans, Martin, Ückert, Frank, Holub, Petr, Hummel, Michael, Swertz, Morris, Proynova, Rumyana, Enckevort, David Van, Jetten, Jonathan +8 moreopenaire +2 more sources
