In vitro Evaluation of Cytotoxic Effects of Methanolic Leaf Extracts of Annona muricata on Oral Squamous Cell Carcinoma-15 Cell Lines and its Effect On Expression of Bcl 2-associated X protein, B-cell C/Lymphoma 2 and p53 Genes. [PDF]
Contemp Clin Dent, 2023 Abstract Background: Due to their wide spectrum of phytochemical components and lack of side effects, the use of plants for the prevention and treatment of cancer has recently attracted increased attention. One among them is Annona muricata, commonly called soursop. According to recent investigations, several types of
Mary SJ +5 more
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Establishment of a specific cell death induction system in Bombyx mori by a transgene with the conserved apoptotic regulator, mouse Bcl‐2‐associated X protein (mouse Bax) [PDF]
Insect Molecular Biology, 2015 AbstractThe induction of apoptosis in vivo is a useful tool for investigating the functions and importance of particular tissues. B‐cell leukaemia/lymphoma 2‐associated X protein (Bax) functions as a pro‐apoptotic factor and induces apoptosis in several organisms.
Megumi Sumitani +7 more
semanticscholar +5 more sources
Screening of BCL-2 associated X protein gene polymorphism associated with scrotal hernia in domesticated swine using polymerase chain reaction-restriction fragment length polymorphism. [PDF]
Asian-Australas J Anim Sci, 2017 Objective This study was conducted to screen scrotal hernia in domesticated swine from selected breeders in the Philippines. This defect is associated with a cytosine to thymine mutation in the BCL-2 associated X protein (BAX) gene of swine. Methods Genetic screening was done by DNA extraction followed by amplification and digestion using polymerase ...
Manalaysay JG +4 more
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Bcl-2-associated transcription factor 1 interacts with fragile X-related protein 1 [PDF]
Acta Biochimica et Biophysica Sinica, 2014 The absence of fragile X mental retardation protein (FMRP) causes fragile X syndrome (FXS), which is the leading cause of hereditary mental retardation. Fragile X-related protein 1 (FXR1P), which plays an important role in normal muscle development, is one of the two autosomal paralogs of FMRP.
Yun Ma +6 more
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Royal Jelly Feeding as a Main Inducer of Bcl-2-associated X Protein in the Peripheral Blood Immune Cells of Patients With Chronic Hepatitis B [PDF]
Avicenna Journal of Clinical Microbiology and Infection, 2022 Aim: Chemokines, cytokines, and their related molecules play crucial roles in the fight against the hepatitis B virus (HBV) and its related complications. Royal jelly (RJ) is considered an immunomodulatory factor for humans. This clinical trial study aimed to explore the RJ effects on the relative expression of CCL2, CCL3, CCL8, IFN-β, NANOG, OCT4, BAX,
Morteza Bahaaldin-Beygi +2 more
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A-Type Cinnamon Procyanidin Oligomers Protect Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Neurotoxicity in Mice Through Inhibiting the P38 Mitogen-Activated Protein Kinase/P53/BCL-2 Associated X Protein Signaling Pathway [PDF]
The Journal of Nutrition, 2020 Parkinson's disease (PD) is a common neurodegenerative disorder. Cinnamon procyanidin oligomers (CPOs) are flavonoids with many claimed health benefits.This study aimed to elucidate the neuroprotection of A-type CPOs (CPO-A) and the underlying mechanisms in cultured cell and animal models of PD.Thirty male mice (C57BL/6, 9-wk old) were assigned to 3 ...
Qi Xu +6 more
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Reconstitution of the anti-apoptotic Bcl-2 protein into lipid membranes and biophysical evidence for its detergent-driven association with the pro-apoptotic Bax protein. [PDF]
PLoS ONE, 2013 The anti-apoptotic B-cell CLL/lymphoma-2 (Bcl-2) protein and its counterpart, the pro-apoptotic Bcl-2-associated X protein (Bax), are key players in the regulation of the mitochondrial pathway of apoptosis. However, how they interact at the mitochondrial
Marcus Wallgren +5 more
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KESANS : International Journal of Health and Science, 2021 Nasopharyngeal cancer is one of the most common types of cancer in Indonesia, especially head and neck cancer. One of the etiology of this cancer is infection with Epstein-Barr virus. Early diagnosis is difficult to establish because the early signs and symptoms of nasopharyngeal carcinoma are not specific.
Puput Angrayany Sapar +2 more
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Food science of animal resources, 2023 This study examined the α-glucosidase inhibitory, and apoptosis- and anti-muscular-related factors of goat meat extracts from forelegs, hind legs, loin, and ribs. The goat meat extracts were evaluated for their α-glucosidase inhibitory activity. The gene and protein expression levels of Bcl-2-associated X (bax), p53, and p21 were examined by reverse ...
Joohyun Kang +4 more
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Journal of Traditional Chinese Medicine, 2017 To investigate the effects of icariin on apoptosis and the expression of Fas, Fas ligand (FasL), B cell lymphoma (Bcl-2), and Bcl-2-associated X protein (Bax) in CD4＋ T lymphocytes from patients with ankylosing spondylitis.Primary cultures of peripheral blood CD4+ T lymphocytes were established and treated with icariin at high, medium, and low doses (0.
Hailong Wang, Quan Jiang, Xinghua Feng
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