Results 41 to 50 of about 213,161 (287)

Impact of neurotrophic factors combination therapy on retinitis pigmentosa

Journal of International Medical Research, 2020
Objective We aimed to determine the location of neurotrophic receptors tropomyosin receptor kinase (Trk)B, TrkC, and ciliary neurotrophic factor receptor (CNTFR)α in the retina of retinal degeneration ( rd ) mice and to explore the dynamic changes of B ...
Xiaobei Yin, Ting He, Rui Chen, Hui Cui, Genlin Li   +4 more
doaj   +1 more source

The roles of apoptosis, autophagy and unfolded protein response in arbovirus, influenza virus, and HIV infections

Virulence, 2019
Virus infection induces different cellular responses in infected cells. These include cellular stress responses like autophagy and unfolded protein response (UPR).
Parvaneh Mehrbod, Sudharsana R. Ande, Javad Alizadeh, Shahrzad Rahimizadeh, Aryana Shariati, Hadis Malek, Mohammad Hashemi, Kathleen K. M. Glover, Affan A. Sher, Kevin M. Coombs, Saeid Ghavami   +10 more
doaj   +1 more source

Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Renal and testicular disorders are primarily associated with oxidative damage and inflammation. Here, alpha-pinene (a type of monoterpene) was investigated for its effect on oxidative/nitrosative stress and the expression of inflammatory ...
Fatemeh Noroozi, Masoumeh Asle Rousta, Rahim Amini, Zeinab Sahraeian   +3 more
doaj   +1 more source

Dissecting the pathways of tumour escape: " question of life and death?" Dissecando os caminhos de escape do tumor: "uma questão de vida e morte?"

Anais Brasileiros de Dermatologia, 2010
Apoptotic pathways are providing important saveguard mechanisms in protection from cancer by eliminating altered and often harmful cells. The disturbances of cell proliferation, differentiation and apoptosis are also found on specific signal-transduction
Georgi Tchernev, Pietro Nenoff
doaj   +1 more source

Selective induction of cell death in melanoma cell lines through targeting of Mcl-1 and A1. [PDF]

, 2012
Melanoma is an often fatal form of skin cancer which is remarkably resistant against radio- and chemotherapy. Even new strategies that target RAS/RAF signaling and display unprecedented efficacy are characterized by resistance mechanisms.
Berking, Carola, Senft Daniela, Robert Besch, Carola Berking, Saskia A Graf, Claudia Kammerbauer, Thomas Ruzicka, Graf, Saskia A., Besch, Robert, Graf Saskia A., Senft, Daniela, Berking Carola, Kammerbauer, Claudia, Daniela Senft, Besch Robert, Kammerbauer Claudia, Ruzicka, Thomas, Saskia A. Graf, Ruzicka Thomas   +18 more
core   +1 more source

Effect of cinnamaldehyde on Bax/Bak and apoptosis of vascular endothelial cells in diabetic ulcers

陆军军医大学学报
Objective To investigate the effects of cinnamic aldehyde (CA) on Bcl-2-associated X protein (Bax) and Bcl-2 homologous antagonist/killer (Bak) in vascular endothelial cells of diabetic ulcer wound tissues, as well as on cell apoptosis.
JIN Zheyu, XIE Chenlei , FAN Xinqi
doaj   +1 more source

Protective Effects of Baicalin on Experimental Myocardial Infarction in Rats

Brazilian Journal of Cardiovascular Surgery
Objective: This study aimed to investigate the protective effects of baicalin on myocardial infarction in rats and explore the related mechanisms. Methods: Fifty Sprague Dawley rats were randomly divided into the control, model, and low-, medium- and ...
Longfei Wang, Yong Li, Shenglan Lin, Zhiqiang Pu, Haiping Li, Zhili Tang   +5 more
doaj   +1 more source

Effect of Icariin on apoptosis and expression of Fas, Fas ligand, B cell lymphoma, and Bcl-2-associated X protein in CD4 + T lymphocytes from patients with ankylosing spondylitis

Journal of Traditional Chinese Medicine, 2017
To investigate the effects of icariin on apoptosis and the expression of Fas, Fas ligand (FasL), B cell lymphoma (Bcl-2), and Bcl-2-associated X protein (Bax) in CD4＋ T lymphocytes from patients with ankylosing spondylitis.Primary cultures of peripheral blood CD4+ T lymphocytes were established and treated with icariin at high, medium, and low doses (0.
Hailong, Wang, Quan, Jiang, Xinghua, Feng   +2 more
openaire   +2 more sources

Comparison of the Effects of Nonprotein and Protein Nitrogen on Apoptosis and Autophagy of Rumen Epithelial Cells in Goats

Animals, 2020
Protein nutrition is particularly important for the self-renewal processes of gastrointestinal epithelial cells. The self-renewal of cells is inseparable from the interaction between apoptosis and autophagy.
Zhiwei Kong, Chuanshe Zhou, Jinhe Kang, Zhiliang Tan   +3 more
doaj   +1 more source

Curcumin: a bioactive compound with molecular targets for human malignancies

Food and Agricultural Immunology, 2023
Cancer is the second leading cause of death in the world and one of the major public health problems. Curcumin has anticancer activity including inducing apoptosis and inhibiting proliferation and invasion of tumours by suppressing a variety of cellular ...
Muhammad Shahbaz, Muhammad Imran, Muzzamal Hussain, Suliman A. Alsagaby, Ushna Momal, Hammad Naeem, Mohamed A. Abdelgawad, Ahmed H. El-Ghorab, Waleed Al Abdulmonem, Ahmed Bilal Waqar, Mohammed M. Ghoneim, Arafa Musa, Entessar Al Jbawi   +12 more
doaj   +1 more source