Results 201 to 210 of about 232,551 (308)

Cold atmospheric plasma combined with nanoparticles in cancer therapy

Interdisciplinary Medicine, EarlyView.
Cold atmospheric plasma (CAP) generates a range of reactive oxygen and nitrogen species (RONS), including singlet oxygen (1O2), hydrogen peroxide (H2O2), hydroxyl radicals (·OH), nitrate (NO3− ${{\text{NO}}_{3}}^{-}$), and nitrite (NO2− ${{\text{NO}}_{2}}^{-}$), which induce oxidative stress and apoptosis in cancer cells.
Yunhao Wang, Fei Cao, Gbenga A. Martins, Qiujie Fang, Yifan Lin, Zhaowei Chen, Guojun Chen, Zhitong Chen   +7 more
wiley   +1 more source

Toxicological Response of the BEAS‐2B Cell After Acute Exposure at the Air–Liquid Interface to Ethylbenzene and m‐Xylene Alone and in Binary Mixtures

Journal of Applied Toxicology, EarlyView.
ABSTRACT Benzene, toluene, ethylbenzene, and xylenes (o‐, m‐, and p‐xylenes) constitute a family, named BTEX, of volatile organic compounds (VOCs) known for its toxicity. This study aimed to study the acute in vitro toxicity of ethylbenzene and m‐xylene on human bronchial epithelial cells exposed at the air–liquid interface (ALI).
Nour Jaber, Claude Emond, Fabrice Cazier, Sylvain Billet   +3 more
wiley   +1 more source

Generation of two human induced pluripotent stem cell lines with BAX and BAK1 double knock-out using CRISPR/Cas9

Stem Cell Research
Bcl-2-associated X protein (BAX) and Blc-2 homologous antagonist killer 1 (BAK) are two pro-apoptotic members of BCL2 family. Here, two BAX/BAK double knock-out human induced pluripotent stem cell lines (iPSC) we generated using CRISPR-Cas9 to generate ...
Katarzyna Anna Ludwik, Lina Hellwig, Tanja Fisch, Jörg Contzen, Claudia Schaar, Philipp Mergenthaler, Harald Stachelscheid   +6 more
doaj  

PLIP 2025: introducing protein-protein interactions to the protein-ligand interaction profiler. [PDF]

Nucleic Acids Res
Schake P, Bolz SN, Linnemann K, Schroeder M.   +3 more
europepmc   +1 more source

Thermal extraction and characterization of pectin from semi‐solid by‐products of the olive oil industry

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The valorization of agro‐industrial by‐products is crucial for promoting sustainability and circular economy. Olive mill semi‐solid by‐products (OMSbP), also known as alperujo, contain valuable bioactive compounds, including pectin, which can be extracted and used in food applications.
Africa Fernandez‐Prior, Luna Barrera‐Chamorro, Elvira Marquez‐Paradas, Carol López‐de‐Dicastillo, Maria C. Millan‐Linares, Alvaro Villanueva‐Lazo, Sergio Montserrat‐de la Paz   +6 more
wiley   +1 more source

Circ_0006646 Promotes the Progression of Osteoarthritis via Upregulating CDH11 Expression in an IGF2BP2‐Dependent Manner

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a common degenerative osteoarthropathy with an unclear pathogenesis. Circular RNA (circRNA) has been reported to be associated with OA progression. This study aims to explore the role and potential mechanism of hsa_circ_0006646 in OA. Interleukin‐1β (IL‐1β)‐induced human chondrocytes were used as the cell model of OA. RT‐
Ming‐Yu Hua, Guo‐Liang Wang, Wen‐Hao Duan, Xiao‐Heng Tang   +3 more
wiley   +1 more source

Protective mechanism of polysaccharides from Phellinus linteus on H9c2 cardiomyocyte injury induced by hypoxia/reoxygenation. [PDF]

BMC Res Notes
Ren X, Mei Q, Zhou Y, Jiang L, Liu F, Wang J.   +5 more
europepmc   +1 more source

LncRNA SOX21‐AS1 Promotes the Progression of Pancreatic Cancer by Sponging miR‐9‐3p and Upregulating YOD1

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pancreatic cancer (PC) is a highly aggressive malignancy of the digestive system. Recent studies have indicated that the long noncoding RNA SOX21‐AS1 is significantly upregulated in PC tissue samples. This study aims to elucidate the biological role and underlying molecular mechanisms of SOX21‐AS1 in PC progression. Quantitative real‐time PCR (
Han‐Bing Xu, Jian‐Tao Han, Cheng‐Peng Zhang, Bin Jiang   +3 more
wiley   +1 more source

TRIM22 promotes glioblastoma development by ubiquitinating Bcl-2. [PDF]

Mol Cell Oncol
Zhang J, Chen Y, Wang G, Huang H, Liu Y, Huang J, Shao J, Jiao J, Cheng C.   +8 more
europepmc   +1 more source

Morroniside Improves Diabetic Osteoporosis via the AGE/RAGE/Wnt/β‐Catenin Signaling Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Morroniside has been shown to possess various pharmacological activities, including anti‐inflammatory and antioxidative effects. This study investigates the potential mechanisms by which morroniside ameliorates diabetic osteoporosis (DOP). In vivo experiments were conducted to evaluate biochemical parameters in rats under different treatment ...
Lu Yang, Kai Wang, Zhao‐Hui Zeng, Hai‐En Zhao, Li‐Min Bai   +4 more
wiley   +1 more source