ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice [PDF]
Forsthoefel, D+7 more
core
ABSTRACT Rhaponitin (Rha) possesses anti‐tumor activity and mediates the transcriptional activity of hypoxia‐inducible factor (HIF)‐1α that affects cisplatin (Cis) resistance. However, whether Rha can lessen Cis resistance in tongue squamous cell carcinoma (TSCC) by mediating HIF‐1α activity is unclear. Cis‐resistant SCC9 (SCC9‐CisR) cells were treated
Yuan Wu+5 more
wiley +1 more source
IFNα-IFITM1-ERK axis in corneal epithelial cell damage: implications for dry eye disease. [PDF]
Peng H, Li S, Zhao G, Peng S, Pang Y.
europepmc +1 more source
Self‐Assembly of Noncanonical Peptides: A New Frontier in Cancer Therapeutics and Beyond
Representative examples of noncanonical peptide assemblies in anticancer therapeutics, biomaterials, regenerative medicine, molecular imaging, and catalysis are discussed, highlighting enzyme‐instructed self‐assembly as a valuable approach for constructing biomimetic and bioinspired materials that bridge the interface between biological systems and ...
Lin Bai, Meihui Yi, Bing Xu
wiley +1 more source
Fenofibrate mitigates the dysfunction of high glucose-driven human retinal microvascular endothelial cells by suppressing NLRP3 inflammasome. [PDF]
Shi Y, Chen HM, Liu AH, Li XR.
europepmc +1 more source
Bax transmembrane domain interacts with prosurvival Bcl-2 proteins in biological membranes
V. Andreu-Férnández+11 more
semanticscholar +1 more source
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley +1 more source
Long non-coding RNA GAS5 promotes neuronal apoptosis in spinal cord injury <i>via</i> the miR-21/PTEN axis. [PDF]
Wang YJ, Zhi ZZ, Liu T, Kang J, Xu GH.
europepmc +1 more source
ABSTRACT Prostate cancer (PCa) is the second leading cause of cancer‐related death among American men, and its long latency offers a window for chemopreventive strategies. Phytochemicals, with their diverse impacts on cancer cell growth and metabolism, represent promising candidates for such strategies.
Chelsea A. Friedman+5 more
wiley +1 more source
Vincamine induces cytoprotective autophagy via regulation of ampk/mtor signaling pathway in gentamicin-induced hepatotoxicity and nephrotoxicity in rats. [PDF]
Abouelhamd A+3 more
europepmc +1 more source