Results 231 to 240 of about 182,114 (270)

HBV HBx protein masks epigenetic reader Spindlin1 via an inter-molecular zinc finger to subvert transcriptional control. [PDF]

open access: yesNat Commun
Clavier A   +8 more
europepmc   +1 more source

Oligomerization process of Bcl-2 associated X protein revealed from intermediate structures in solution.

Physical Chemistry Chemical Physics, 2017
Linear oligomerization of ditopic BAX-dimers into tri-dimer helical units then into a rod-like structure, as revealed using integrated ESR/SAXS/MD analyses.
O. Shih   +5 more
semanticscholar   +3 more sources

Protective mechanism of gallic acid and its novel derivative against ethanol-induced gastric ulcerogenesis: Involvement of immunomodulation markers, Hsp70 and Bcl-2-associated X protein.

International Immunopharmacology, 2013
Some phytochemicals demonstrate gastroprotective effects by inhibiting gastric acid secretion or through antioxidant action. One of these antioxidant phytochemicals which have been studied is gallic acid. However, its mechanism in the treatment and prevention of gastric ulcer remains unclear.
S. Abdelwahab
semanticscholar   +3 more sources

BIM (BCL-2 interacting mediator of cell death) SAHB (stabilized α helix of BCL2) not always convinces BAX (BCL-2-associated X protein) for apoptosis.

Journal of Molecular Graphics and Modelling, 2016
The interaction of BAX (BCL-2-associated X protein) with BIM (BCL-2 interacting mediator of cell death) SAHB (stabilized α helix of BCL2) directly initiates BAX-mediated mitochondrial apoptosis. This molecular dynamics study reveals that BIM SAHB forms a stable complex with BAX but it remains in a non-functional conformation.
S. Verma   +5 more
semanticscholar   +3 more sources

Near-infrared-inducible Bcl-2-associated X Protein System for Apoptosis Regulation in Vivo

Chemical Engineering Journal, 2023
Shiqi Lin   +5 more
semanticscholar   +2 more sources

Long noncoding RNA DINO (damage induced noncoding) represses the development of gastric cancer by modulating p21 and Bcl‐2 Associated X Protein (Bax) expression

Journal of Cellular Biochemistry, 2019
AbstractlncRNAs are responsible for a variety of diseases, including gastric cancer (GC). Many recent studies have reported that lncRNAs can serve as crucial regulators of various genes. Nevertheless, the biological function of lncRNA damage induced noncoding (DINO) remained poorly investigated in GC.
Qinqiang Liu   +4 more
openaire   +2 more sources

Melatonin attenuates hippocampal neuron apoptosis and oxidative stress during chronic intermittent hypoxia via up-regulating B-cell lymphoma-2 and down-regulating B-cell lymphoma-2-associated X protein.

Saudi Medical Journal, 2013
OBJECTIVE To investigate the neuroprotective effect of melatonin against chronic intermittent hypoxia (CIH), the major pathophysiologic features of obstructive sleep apnea syndrome.
Xiaoqin Tan, Xue-ling Guo, Hui-guo Liu
semanticscholar   +1 more source

Establishment of a specific cell death induction system in Bombyx mori by a transgene with the conserved apoptotic regulator, mouse Bcl‐2‐associated X protein (mouse Bax)

Insect Molecular Biology, 2015
Abstract The induction of apoptosis in vivo is a useful tool for investigating the functions and importance of particular tissues. B‐cell leukaemia/lymphoma 2‐associated X protein (Bax) functions as a pro‐apoptotic factor and induces apoptosis in several organisms.
M, Sumitani   +7 more
openaire   +2 more sources

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