Results 281 to 290 of about 232,551 (308)

Oligomerization process of Bcl-2 associated X protein revealed from intermediate structures in solution

open access: closedPhysical Chemistry Chemical Physics, 2017
Linear oligomerization of ditopic BAX-dimers into tri-dimer helical units then into a rod-like structure, as revealed using integrated ESR/SAXS/MD analyses.
Orion Shih   +5 more
semanticscholar   +5 more sources

Protective mechanism of gallic acid and its novel derivative against ethanol-induced gastric ulcerogenesis: Involvement of immunomodulation markers, Hsp70 and Bcl-2-associated X protein

open access: closedInternational Immunopharmacology, 2013
Some phytochemicals demonstrate gastroprotective effects by inhibiting gastric acid secretion or through antioxidant action. One of these antioxidant phytochemicals which have been studied is gallic acid. However, its mechanism in the treatment and prevention of gastric ulcer remains unclear.
Siddig İbrahim Abdelwahab
semanticscholar   +5 more sources

Near-infrared-inducible Bcl-2-associated X protein system for apoptosis regulation in vivo

open access: closedChemical Engineering Journal, 2023
Shiqi Lin   +5 more
semanticscholar   +3 more sources

Long noncoding RNA DINO (damage induced noncoding) represses the development of gastric cancer by modulating p21 and Bcl‐2 Associated X Protein (Bax) expression

open access: closedJournal of Cellular Biochemistry, 2019
AbstractlncRNAs are responsible for a variety of diseases, including gastric cancer (GC). Many recent studies have reported that lncRNAs can serve as crucial regulators of various genes. Nevertheless, the biological function of lncRNA damage induced noncoding (DINO) remained poorly investigated in GC.
Qinqiang Liu   +4 more
openalex   +4 more sources

BIM (BCL-2 interacting mediator of cell death) SAHB (stabilized α helix of BCL2) not always convinces BAX (BCL-2-associated X protein) for apoptosis

open access: closedJournal of Molecular Graphics and Modelling, 2016
The interaction of BAX (BCL-2-associated X protein) with BIM (BCL-2 interacting mediator of cell death) SAHB (stabilized α helix of BCL2) directly initiates BAX-mediated mitochondrial apoptosis. This molecular dynamics study reveals that BIM SAHB forms a stable complex with BAX but it remains in a non-functional conformation.
Sharad Verma   +5 more
openalex   +4 more sources

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