Results 161 to 170 of about 408,548 (333)

Detection of Bcl-2 translocation in pancreatic cancer in Iranian patients [PDF]

, 2018
Background and Purpose: Pancreatic cancer is one of the most leading causes of cancer-related deaths. Considering the role of Bcl-2 family gene in apoptosis that are known to be over-expressed in most cancers, this study focused on the detection of Bcl-2
Abdolhamid Angaji, Seyed, Gordehie, Susan, Khanaki, Mahmoud, Marandi, Vahid, Sheikhnejad, Reza   +4 more
core  

Hybridization of Homogeneous and Heterogeneous Catalysis to Develop a Novel Biocatalyst via Immobilization of Lipase on Surface Modified Mesoporous Silica Towards Biodiesel Synthesis Application

Advanced Energy and Sustainability Research, EarlyView.
The 3‐(methacryloyloxy)propyltrimethoxysilane surface functionalized SBA‐15 (MP‐SBA‐15) is used for the first time as a lipase carrier. The immobilized CAL‐B exhibits high thermal stability and superior catalytic activity. CAL‐B/SBA‐15 suggests that optimum hydrophobicity gives better catalytic activity.
Murugappan N., Ayumi Sato, Jiachen Ge, Arisa Yamada, Makoto Onaka, Yuki Nakamura, Masaru Ogura   +6 more
wiley   +1 more source

Bcl-2 dependent modulation of Hippo pathway in cancer cells

Cell Communication and Signaling
Introduction Bcl-2 and Bcl-xL are the most studied anti-apoptotic members of Bcl-2 family proteins. We previously characterized both of them, not only for their role in regulating apoptosis and resistance to therapy in cancer cells, but also for their ...
Simona D’Aguanno, Matteo Brignone, Stefano Scalera, Martina Chiacchiarini, Marta Di Martile, Elisabetta Valentini, Francesca De Nicola, Alessia Ricci, Fabio Pelle, Claudio Botti, Marcello Maugeri-Saccà, Donatella Del Bufalo   +11 more
doaj   +1 more source

Combination therapy of metformin with sodium selenite reverses effects of monotherapy on nitric oxide production, IL-1β and TNF-α release, and upregulates relative expression of Bcl-2 by LPS-activated human primary monocytes in T-cell acute lymphoblastic leukemia [PDF]

, 2022
Fella Rostane, Nidel Sari, Ilyes Bali, Rabia Messali, Zeyneb Hadjidj, Maroua Miliani, Imène Belhassena, Charazed El Mezouar, Mourad Aribi   +8 more
openalex   +1 more source

Expanding the Genotype–Phenotype Correlation of Marden–Walker Syndrome due to PIEZO2 Gene Variants: A Case Report From Brazil

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Marden–Walker syndrome (MWS; OMIM 248700) is an extremely rare congenital disorder characterized by multiple joint contractures, craniofacial dysmorphism, neurological abnormalities, and multisystem involvement. Although historically diagnosed on clinical grounds, only a few cases have been molecularly confirmed.
Guilherme Sotto Battiston, Carolina de Souza Araujo, Fernanda Araujo Romera, André Luis Ferreira, Érica Trovisco Martins, Carolina Galhós de Aguiar, José Eduardo Mourão Santos, Rodrigo Ragazzini, Daniela Testoni Costa‐Nobre, Ana Claudia Yoshikumi Prestes, Allan Chiaratti de Oliveira, Eduardo Perrone, Débora Gusmão Melo, Anne Caroline Barbosa Teixeira, Antonio Victor Campos Coelho, Caio Robledo D’Angioli Costa Quaio, Carolina Araujo Moreno, Eduardo Perrone, Jose Bandeira do Nascimento Junior, Jessica Grasiela Araujo Espolaor, Joana Rosa Marques Prota, Joao Bosco de Oliveira Filho, Jose Ricardo Magliocco Ceroni, Kelin Chen, Letícia Torres Ferreira, Lucas Santos de Santana, Luciana Souto Mofatto, Luiza do Amaral Virmond, Marina de Franca Basto Silva, Michele Patricia Migliavacca, Renata Moldenhauer Minillo, Renata Yoshiko Yamada, Roberta Sitnik, Tatiana Ferreira de Almeida, Thiago Yoshinaga Tonholo Silva, Vivian Pedigone Cintra   +35 more
wiley   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Reduction of Ribonucleotide Reductase Subunit RRM2 Potentially Impairs Gut Function of Woody Breast Broilers

Animal Research and One Health, EarlyView.
Woody breast compromises meat quality leading to reduced consumer appeal. Although its causes are unclear, improvements observed with certain dietary supplements suggest that gut health may influence woody breast development. Ribonucleotide reductase subunit RRM2 is vital for mitochondrial function and gastrointestinal integrity, and alteration in its ...
Majid Shakeri, Elizabeth Ziabtchenko, Janghan Choi, Caitlin E. Harris, Richard J. Buhr, Trevor R. Mitchell, Byungwhi Kong, Hong Zhuang, Brian Bowker   +8 more
wiley   +1 more source

Overexpression of Bcl-2 in hepatocytes protects against injury but does not attenuate fibrosis in a mouse model of chronic cholestatic liver disease [PDF]

, 2010
Claudia Mitchell, Meriem Mahrouf‐Yorgov, Alicia Mayeuf-Louchart, Marie‐Anne Robin, Abdellah Mansouri, Bernard Fromenty, Hélène Gilgenkrantz   +6 more
openalex   +1 more source

Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus

Animal Research and One Health, EarlyView.
The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary, Nidhishree N. S, Rakesh Kumar Pundir, Muhasin Asaf V. N, Anamika Mishra, Ashwin Ashok Raut, Megha Agarwal, Amod Kumar   +7 more
wiley   +1 more source

Transformation of Bone Marrow B-Cell Progenitors by E2A-HLF Requires Coexpression of BCL-2

, 2002
Kevin S. Smith, Joon Whan Rhee, Michael L. Cleary   +2 more
openalex   +2 more sources