Results 171 to 180 of about 408,548 (333)

Synergistic antitumoral activity and induction of apoptosis by novel pan Bcl-2 proteins inhibitor apogossypolone with adriamycin in human hepatocellular carcinoma [PDF]

, 2008
Jin-xia Mi, Guang-feng Wang, Heng-bang Wang, Xiao-Qing Sun, Xin-yan Ni, Xiong-wen Zhang, Jia-ming Tang, Da-Jun Yang   +7 more
openalex   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Dietary Glutamine Supplementation Alleviated Rumen Epithelium Oxidative Damage and Apoptosis Induced by Feed Restriction via Maintaining Mitochondrial Homeostasis in Female Yaks

Animal Research and One Health, EarlyView.
Dietary glutamine (Gln) supplementation increased the ATP levels and promoted cell proliferation in the rumen epithelium of feed‐restricted yaks. Besides, Gln inhibited ROS accumulation and reduced oxidative damage and apoptosis in the rumen epithelium of feed‐restricted yaks.
Ziqi Yue, Shanpeng Ke, Liyuan Shi, Rui Hu, Zhisheng Wang, Quanhui Peng, Huawei Zou, Jianxin Xiao, Yahui Jiang, Fali Wu, Yiping Tang   +10 more
wiley   +1 more source

The Trophic Action of IL-7 on Pro-T Cells: Inhibition of Apoptosis of Pro-T1, -T2, and -T3 Cells Correlates with Bcl-2 and Bax Levels and Is Independent of Fas and p53 Pathways [PDF]

, 1998
Kyungjae Kim, Chong‐Kil Lee, Thomas J. Sayers, Kathrin Muegge, Scott K. Durum   +4 more
openalex   +1 more source

Figure S5 from AZD4320, A Dual Inhibitor of Bcl-2 and Bcl-x_L, Induces Tumor Regression in Hematologic Cancer Models without Dose-limiting Thrombocytopenia

, 2023
Srividya B. Balachander, Steven W. Criscione, Kate F. Byth, Justin Cidado, Ammar Adam, Paula Lewis, Terry Macintyre, Shenghua Wen, Deborah Lawson, Kathleen A. Burke, Tristan Lubinski, Jeffrey Tyner, Stephen E. Kurtz, Shannon K. McWeeney, Jeffrey Varnes, R. Bruce Diebold, Thomas W. Gero, Stephanos Ioannidis, Edward J. Hennessy, William McCoull, Jamal Saeh, Areya Tabatabai, Omid Tavana, Nancy Su, Alwin G. Schuller, Mathew J. Garnett, Patricia Jaaks, Elizabeth A. Coker, Gareth P. Gregory, Andrea Newbold, Ricky W. Johnstone, Eric T. Gangl, Martin Wild, Michael Zinda, J. Paul Secrist, Barry R. Davies, Stephen E. Fawell, Francis D. Gibbons   +37 more
openalex   +1 more source

Bacterial Pigments as Potential Antitumor Agents Against Gastrointestinal Cancers: A Comprehensive Systematic Review

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara, Ricardo F. S. Pereira, Carla C. C. R. de Carvalho, Jose Prados, Consolación Melguizo, Raul Ortiz   +5 more
wiley   +1 more source

Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity

, 1995
Shinichi Takayama, Takaaki Sato, S Krajewski, Kristine Kochel, Shinji Irie, Juan A Milian, John C. Reed   +6 more
openalex   +1 more source

Multifunctional H2S‐activated metal‐organic framework systems for targeted colorectal cancer imaging and synergistic copper‐induced tumor regression

BMEMat, EarlyView.
The in situ reaction of Cu‐MOFs with endogenous H2S enabled PA imaging and facilitated combined PTT/chemotherapy for colorectal cancer therapy. Abstract Stimuli‐responsive nanomaterials offer significant potential for enhancing diagnostic accuracy, optimizing therapeutic efficacy, and advancing precision theranostics.
Nannan Zheng, Qinghui Wang, Zhiyue Cao, Chao Yu, Renkai Zhang, Kaiyan Xiang, Haoguang Wu, Kai Li, Qianqian Ni, Qiuyue Ma, Jing Mu, Xiaoyuan Chen, Liangcan He, Shaoqin Liu   +13 more
wiley   +1 more source

Bcl-2 modifying factor (Bmf): "a mysterious stranger" in the Bcl-2 family proteins. [PDF]

Cell Death Differ
Pervushin NV, Nilov DK, Zhivotovsky B, Kopeina GS.   +3 more
europepmc   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source