Results 141 to 150 of about 145,113 (281)
ABSTRACT Diflubenzuron is used as an insect growth inhibitor, and its potential risk to human health was raised owing to the possibility of environmental residues and human exposure. This study aimed to investigate the toxic mechanism of diflubenzuron on trophoblastic cells such as HTR8/SVneo and JEG‐3 cells. We investigated mitochondrial function, Ca2+
Miji Kim +4 more
wiley +1 more source
Effect of aerobic exercise on some factors of cardiac apoptosis in male rats
Background: Cardiac apoptosisplays an important role in myocardial diseases. Current evidence suggests that exercise training may modify some apoptosis-related signaling in myocardium.
Sadighi A +3 more
doaj
Abstract Prostatic stromal tumor of uncertain malignant potential (STUMP) is a rare neoplasm arising from specialized prostatic stromal cells with a broad range of histologic patterns and unpredictable clinical behavior. It is often challenging to distinguish STUMP from prostatic stromal sarcoma due to morphological similarities, necessitating specific
Ibrahim A. Khalil +7 more
wiley +1 more source
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding +10 more
wiley +1 more source
We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen +9 more
wiley +1 more source
ABSTRACT Objectives Acquired cholesteatoma is an abnormal and invasive growth of keratinized squamous epithelial cells in the middle ear. The study aims to explore the role of exosomal miRNAs in the pathogenesis of acquired cholesteatoma and their potential in clinical application.
Qi Tang +12 more
wiley +1 more source
Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu +3 more
wiley +1 more source

