Results 211 to 220 of about 150,149 (335)
Supplementary Figure 3 from Targeting BCL2 Overcomes Resistance and Augments Response to Aurora Kinase B Inhibition by AZD2811 in Small Cell Lung Cancer
, 2023 Kavya Ramkumar, Azusa Tanimoto, Carminia M. Della Corte, C. Allison Stewart, Qi Wang, Li Shen, Robert J. Cardnell, Jing Wang, Urszula M. Polanska, Courtney L. Andersen, Jamal Saeh, J. Elizabeth Pease, Jon Travers, Giulia Fabbri, Carl M. Gay, Jelena Urosevic, Lauren A. Byers +16 moreopenalex +1 more sourceNewly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators
The FEBS Journal, EarlyView.Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.Janine Fichtner, Yan Yan Beer, H. G. Mauricio Ramm, Sabrina Mühlen, Frank Surup, Jennifer Herrmann, Toni Luise Meister, Stephanie Pfaender, Ursula Bilitewski, Mark Brönstrup, Rolf Müller, Manfred Wirth, Eeva‐Liisa Eskelinen, Ingo Schmitz +13 morewiley +1 more sourceEpigenetic Regulation and Gene Expression Profiles in Cervical Swabs: Toward Non-Invasive Biomarkers of Cervical Lesion Progression. [PDF]
EpigenomesKašubová I, Hornáková A, Kotúľová L, Rokos T, Kolková Z, Kapinová A, Pribulová T, Kozubík E, Kalman M, Biringer K, Kúdela E, Holubeková V. +11 moreeuropepmc +1 more sourceData from Combinatorial BCL2 Family Expression in Acute Myeloid Leukemia Stem Cells Predicts Clinical Response to Azacitidine/Venetoclax
, 2023 Alexander Waclawiczek, Aino‐Maija Leppä, Simon Renders, Karolin Stumpf, Cecilia Reyneri, Barbara Betz, Maike Janssen, Rabia Shahswar, Elisa Donato, Darja Karpova, Vera Thiel, Julia M. Unglaub, Susanna Grabowski, Stefanie Gryzik, Lisa Vierbaum, Richard F. Schlenk, Christoph Röllig, Michael Hundemer, Caroline Pabst, Michael Heuser, Simon Raffel, Carsten Müller‐Tidow, Tim Sauer, Andreas Trumpp +23 moreopenalex +1 more sourceCellular Morphometric Analysis (CellMorph)—a comprehensive imaging‐based tool for quantifying cellular phenotype heterogeneity and dynamics across biological processes
The FEBS Journal, EarlyView.CellMorph is a groundbreaking tool that allows researchers to analyze multiple features from single cells, including cell size and shape, cytosolic staining and subcellular texture, nuclear staining, and morphometry. By evaluating images from both bright‐field and fluorescence microscopy, it also tracks changes in living cells during key processes such Henrique Quaiato de Oliveira, Solon Andrades da Rosa, Luiza Cherobini Pereira, Laura Boose de Mendonça, Juliete Scholl, Fabrício Figueiró, Thais Cardoso Bitencourt, Davi Piovesan Echevarria, João Luiz Aldinucci Buzzo, Jessica Boschini D'Agostin, Danieli Rosane Dallemole, Carolina Oliveira, Fernanda Simas, Fernanda Saez‐Calazans, Débora Santos‐Sousa, Guido Lenz, Eduardo C. Filippi‐Chiela +16 morewiley +1 more source