Results 281 to 290 of about 150,149 (335)

BCL2-associated X protein (BAX); BCL2-like 11 (apoptosis facilitator) (BCL2L11; BIM) [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Antioxidant and anticancer potentiality of F13 fraction of Pleurotus sajar caju against cancer cell lines and in silico analysis. [PDF]

Sci Rep
Pandey K, Ghosh M, Ghosh SK.
europepmc   +1 more source

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

Advanced Science, Volume 13, Issue 7, 3 February 2026.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu, Yawei Shen, Robert J. Barndt, Karim Sallam, Ying Tang, Cameron E. Brown, Xiao Li, Stephen Y. Chan, Joseph C. Wu, Qing Liu, Haodi Wu   +10 more
wiley   +1 more source

CSNK1D inhibition suppresses head and neck squamous cell carcinoma progression through SHH and PTCH1 pathway. [PDF]

Cell Death Dis
Yang L, Li X, Zhu Y, Zhang Y, Liu Z, Lin C, Jiang C, Su YX, Ji T, Wang Y, Gao J, Ye J.   +11 more
europepmc   +1 more source

C-MYC and BCL2 Expression in Normal Tissue Around Proliferative Breast Conditions in Relation to ER, PR in a Sample of Iraqi Women

, 2018
Ahmed F. Hameed, Mustafa Mohammed Ibraheem, Basim Sh. Ahmed   +2 more
openalex   +1 more source

Engineering an Anaerobic Microenvironment to Empower Hydrogenase‐Catalyzed Hydrogen Therapy for Diabetic Wound Healing

Aggregate, Volume 7, Issue 2, February 2026.
A smart peptide hydrogel integrated with light‐responsive silver nanoclusters establishes a localized anaerobic niche, enabling hydrogenase function in oxygen‐rich biological environments. The system achieves sustained visible‐light‐driven H2 production, effectively scavenges reactive oxygen species, modulates immune responses, and significantly ...
Haishuo Ji, Yaling Wang, Kexin Yao, Junjie Li, Hang Luo, Wangzhe Li, Yanxin Gao, Wenjin Li, Qi Xiao, Tin Pou Lai, Chunxiao Chen, Xueying Li, Qian Peng, Chunqiu Zhang, Baofa Sun, Liyun Zhang   +15 more
wiley   +1 more source

The protective role of dietary nutrients in mitigating asthma risks induced by indoor air pollutants: a comparative toxicogenomics perspective. [PDF]

Sci Rep
Sun Z, Yang Y, Lin D, Liu Y, Su Y, Wang B.   +5 more
europepmc   +1 more source

An Anoikis Resistance Phenotype Converged to Immune Dysfunction and Resistance to Immune Checkpoint Blockades in Gastric Cancer

Cancer Innovation, Volume 5, Issue 1, February 2026.
Gastric cancer (GC) has high global incidence and mortality, with most cases diagnosed at advanced stages. Immunotherapy, particularly immune checkpoint blockers (ICBs), has shown promise, but not all patients benefit. This study applied consensus clustering based on anoikis‐related genes (ANRGs) to classify GC into two subclusters.
Xing Cai, Jinru Yang, Fangyuan Zhang, Fuwang Xu, Yuan Fang, Zongbi Yi   +5 more
wiley   +1 more source

The Evolution of Gallic Acid in Aged White Tea and Its Potential Anti-Aging Mechanisms: An Integrated Study Combining Network Pharmacology and Computer Simulation. [PDF]

Food Sci Nutr
Tuo Y, Lu X, Song Q, Huang R, Huang J, Sun H, Liao N, Shi Y, Wu L, Lin J, Hu Y.   +10 more
europepmc   +1 more source