Bcr-Abl Exerts Its Antiapoptotic Effect Against Diverse Apoptotic Stimuli Through Blockage of Mitochondrial Release of Cytochrome C and Activation of Caspase-3 [PDF]
Gustavo P. Amarante‐Mendes+6 more
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INVESTIGATING ALLOSTERIC REGULATION OF ABL AND BCR-ABL KINASES: IMPLICATIONS FOR SMALL MOLECULE INHIBITORS [PDF]
BCR-ABL is the oncogenic protein-tyrosine kinase responsible for the pathogenesis of chronic myelogenous leukemia (CML). Clinical management of CML has been revolutionized by imatinib, a selective ATP-competitive inhibitor of BCR-ABL kinase activity ...
PANJARIAN, SHOGHAG
core +1 more source
Spectrum of BCR-ABL mutations in Azerbaijanian imatinib-resistant patients with chronic myeloid leukemia. [PDF]
Hasanova A+5 more
europepmc +1 more source
Kinetics of increasing BCR-ABL transcript numbers in chronic myeloid leukemia patients who relapse after bone marrow transplantation [PDF]
Feng Lin+3 more
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BCR/ABL rearrangement and leukemia phenotype [PDF]
SAGLIO, Giuseppe+3 more
openaire +4 more sources
Differential vascular endothelial cell toxicity of established and novel BCR-ABL tyrosine kinase inhibitors. [PDF]
Wang Y+7 more
europepmc +1 more source
TLS/FUS, a pro-oncogene involved in multiple chromosomal translocations, is a novel regulator of BCR/ABL-mediated leukemogenesis [PDF]
Danilo Perrotti
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Inhibition of BCR-ABL Expression With Antisense Oligodeoxynucleotides Restores β1 Integrin-Mediated Adhesion and Proliferation Inhibition in Chronic Myelogenous Leukemia Hematopoietic Progenitors [PDF]
Ravi Bhatia, Catherine M. Verfaillie
openalex +1 more source
The BCR-ABL oncogene requires both kinase activity and src-homology 2 domain to induce cytokine secretion [PDF]
Anderson Sm, J Mladenovic
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