Results 161 to 170 of about 68,946 (284)

A novel maxizyme vector targeting a bcr-abl fusion gene induced specific cell death in Philadelphia chromosome-positive acute lymphoblastic leukemia [PDF]

, 2004
Yasushi Soda
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AMN107, a novel aminopyrimidine inhibitor of p190 Bcr‐Abl activation and of in vitro proliferation of Philadelphia‐positive acute lymphoblastic leukemia cells [PDF]

, 2005
Srđan Verstovšek, Mirna Golemović, Hagop M. Kantarjian, T Manshouri, Zeev Estrov, Paul W. Manley, Tong Sun, Ralph B. Arlinghaus, Leila Alland, Margaret Dugan, Jorge E. Cortés, Francis J. Giles, Miloslav Beran   +12 more
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New treatment regimen for acute megakaryoblastic leukemia with BCR-ABL positive: case report and literature review [PDF]

, 2021
Huafei Shen, Yuanfei Shi, Xiaolong Zheng, Jie Jin, Wanzhuo Xie   +4 more
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Durable responses to imatinib in patients with PDGFRB fusion gene–positive and BCR-ABL–negative chronic myeloproliferative disorders [PDF]

, 2006
Marianna Dávid, Nicholas C.P. Cross, Sonja Burgstaller, Andrew Chase, Claire Curtis, Raymond Dang, Martine Gardembas, John M. Goldman, Francis Grand, George S. Hughes, Françoise Huguet, Louise Lavender, Grant A. McArthur, François Xavier Mahon, Giorgio Massimini, Junia V. Melo, Philippe Rousselot, R. Russell‐Jones, John F. Seymour, Graeme Smith, Alastair Stark, Katherine Waghorn, Zariana Nikolova, Jane F. Apperley   +23 more
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Preclinical Evaluation of a Novel Small Molecule Inhibitor of LIM Kinases (LIMK) CEL_Amide in Philadelphia-Chromosome Positive (BCR::ABL+) Acute Lymphoblastic Leukemia (ALL) [PDF]

, 2022
Jeannig Berrou, Mélanie Dupont, Hanane Djamai, Emilie Adicéam, Véronique Parietti, Anna Kaci, Emmanuelle Clappier, Jean‐Michel Cayuela, André Baruchel, Fabrice Paublant, Renaud Prudent, Jacques Ghysdael, Claude Gardin, Hervé Dombret, Thorsten Braun   +14 more
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Patients in Focus: What's Relevant for Chronic Myeloid Leukaemia and Philadelphia Chromosome-Positive Acute Lymphoblastic Leukaemia?

European Medical Journal Hematology, 2017
This symposium was dedicated to discussing BCR-ABL-positive chronic myeloid leukaemia (CML) and Philadelphia-positive acute lymphoblastic leukaemia (Ph+ALL).
Michele Baccarani, Eduardo Olavarria, Hugues de Lavallade, Delphine Rea, Giovanni Martinelli   +4 more
doaj  

Philadelphia-positive patients who already harbor imatinib-resistant Bcr-Abl kinase domain mutations have a higher likelihood of developing additional mutations associated with resistance to second- or third-line tyrosine kinase inhibitors [PDF]

, 2009
Simona Soverini, Alessandra Gnani, Sabrina Colarossi, Fausto Castagnetti, Elisabetta Abruzzese, Stefania Paolini, Serena Merante, Ester Orlandi, Silvia De Matteis, Antonella Gozzini, Ilaria Iacobucci, Francesca Palandri, Gabriele Gugliotta, Cristina Papayannidis, Angela Poerio, Marilina Amabile, Daniela Cilloni, Gianantonio Rosti, Michele Baccarani, Giovanni Martinelli   +19 more
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Targeting Hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL-positive chronic myeloid leukemia

Autophagy, 2015
Xian Zeng, Hui Zhao, Yubin Li, Jiajun Fan, Yun Sun, Shao-Kai Wang, Ziyu Wang, P. Song, D. Ju   +8 more
semanticscholar   +1 more source

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias.

, 1991
Alexander J. Muller, Judy Young, Ann Marie Pendergast, Mark Pondel, NR Landau, Dan R. Littman, Owen N. Witte   +6 more
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Neue Ansätze des molekularen Targetings bei der Philadelphia-Chromosom-positiven Leukämie [PDF]

, 2011
In Philadelphia Chromosome (Ph) positive ALL and CML the fusion between BCR and ABL leads to the BCR/ABL fusion proteins, which induces the leukemic phenotype because of the constitutive activation of multiple signaling pathways down-stream to the ...
Mian, Afsar Ali
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