Results 161 to 170 of about 288,388 (279)

<i>BCR::ABL1</i> Mutational Profiling in US Patients With Chronic-phase Chronic Myeloid Leukemia on Tyrosine Kinase Inhibitors. [PDF]

Cancer Diagn Progn
Haddad FG, Jabbour EJ, Gutkin SW, Pathak AK, Zhai Y, Kantarjian HM.   +5 more
europepmc   +1 more source

Chemotherapy‐driven expression of WNT ligands in bone marrow stromal cells contributes to chemoresistance in acute lymphoblastic leukaemia

British Journal of Haematology, EarlyView.
Chemotherapy‐induced WNT ligand secretion by bone marrow (BM) stroma drives acute lymphoblastic leukaemia (ALL) chemoresistance. WNT pathway inhibition disrupts this cross‐talk and restores therapeutic response, highlighting WNT inhibitors as a promising strategy to prevent relapse in ALL.
Foteini Kalampalika, Amanda Jiménez‐Pompa, Raúl Sánchez‐Lanzas, Bela Patel, Miguel Ganuza   +4 more
wiley   +1 more source

Case Report: Co-existence of <i>BCR::PDGFRA</i> gene fusion and <i>PDGFRA</i> variants in myeloid neoplasm with persistent leukocytosis, large splenomegaly, and eosinophilia. [PDF]

Front Oncol
Xiao Z, Lu C, Zhang P, Han N, He X, Zhang J, Feng Y, Guan M, Ouyang L, Gao Y, Li Y.   +10 more
europepmc   +1 more source

3D‐printed model for resection of positive surgical margins in robot‐assisted prostatectomy

BJU International, Volume 135, Issue 4, Page 657-667, April 2025.
Objectives To improve precision of secondary resection (SR) after positive surgical margin (PSM) detection by frozen section (FS) during nerve‐sparing (NS) robot‐assisted radical prostatectomy (RARP) by employing a personalised three‐dimensional (3D)‐printed prostate model derived from pelvic magnetic resonance imaging (MRI).
Christian Engesser, Philipp Brantner, Brigitta Gahl, Matthias Walter, Julian Gehweiler, Helge Seifert, Svetozar Subotic, Cyrill Rentsch, Christian Wetterauer, Lukas Bubendorf, Tatjana Vlajnic, Abolfazl Hosseini, Jan Ebbing   +12 more
wiley   +1 more source

Prognostic value of tumour volume based on [¹⁸F]PSMA-1007 PET/CT in prostate cancer. [PDF]

EJNMMI Rep
Ingvar J, Wittgren J, Sverrisdottir V, Trägårdh E, Bjartell A.   +4 more
europepmc   +1 more source

The cost‐effectiveness of intraoperative margin assessment strategies during radical prostatectomy

BJU International, EarlyView.
Objective To determine whether current intraoperative margin assessment (IOMA) techniques (such as Neurovascular Structure Adjacent Frozen‐section Examination [NeuroSAFE] or confocal laser microscopy [CLM]) used during radical prostatectomy (RP) to enhance nerve‐sparing surgery (NSS) while reducing positive surgical margins (PSMs) justify their extra ...
Joost van Drumpt, Tim Govers, Ricardo Almeida‐Magana, Diederik Baas, Aiman Haider, Michiel Sedelaar, Greg Shaw, Diederik Somford   +7 more
wiley   +1 more source

Dasatinib Associated Pleural Complications- A Case Series. [PDF]

Respirol Case Rep
Vazhoor V, Pavithran SK, Unni M, Mehta A, Pavithran K.   +4 more
europepmc   +1 more source

Impact of positive surgical margins on biochemical recurrence and metastases after radical prostatectomy

BJU International, EarlyView.
Objectives To evaluate the impact of the presence, extent and location of positive surgical margins (PSMs) on the risk of biochemical recurrence (BCR) and metastases in a nationwide cohort of patients who underwent radical prostatectomy (RP) and had 5 years of follow‐up.
Joost van Drumpt, Diederik Baas, Katja Aben, Arno van Leenders, Lambertus Kiemeney, Michiel Sedelaar, Peter Mulders, Jean‐Paul van Basten, Inge van Oort, Berdine Heesterman, Diederik Somford   +10 more
wiley   +1 more source

Assessing the utility of bulbocavernosus reflex for predicting urological outcome in children with spinal dysraphism surgery. [PDF]

Childs Nerv Syst
Saenz A, Jankovic I, Mann C, Lee A, Desai D, Tahir Z, Pang D, Thompson D.   +7 more
europepmc   +1 more source

Identification of novel FGFR2::TXLNB Fusion in a polymorphous low‐grade neuroepithelial tumor of the young

Brain Pathology, EarlyView.
We report a novel FGFR2::TXLNB fusion in a child with hippocampal PLNTY. This fusion likely drives tumorigenesis via homodimerization and activation of MAPK/PI3K pathways, expanding PLNTY's molecular spectrum and suggesting a potential therapeutic target.
Sha‐Sha Hu, Tian‐Yuan Tan, Wei Yan, Bo Wang   +3 more
wiley   +1 more source