Activation of adenosine A2A receptors induces TrkB translocation and increases BDNF-mediated phospho-TrkB localization in lipid rafts : implications for neuromodulation [PDF]
, 2010 Copyright © 2010 the authorsBrain-derived neurotrophic factor (BDNF) signaling is critical for neuronal development and transmission. Recruitment of TrkB receptors to lipid rafts has been hown to be necessary for the activation of specific signaling ...
Assaife-Lopes, Natália +5 more
core +1 more source
Evaluation of serum brain-derived neurotrophic factor levels in preterm and term neonates and its association with hyperbilirubinemia [PDF]
Journal of Krishna Institute of Medical Sciences University, 2022 Background: Neonatal hyperbilirubinemia is the most common cause of hospital admission in the first month of life. Maternal, neonatal, and prenatal factors affect the severity of neonatal hyperbilirubinemia.
Jayashree R +5 more
doaj
The immediate early gene Egr3 Is required for hippocampal induction of Bdnf by electroconvulsive stimulation [PDF]
, 2018 Early growth response 3 (Egr3) is an immediate early gene (IEG) that is regulated downstream of a cascade of genes associated with risk for psychiatric disorders, and dysfunction of Egr3 itself has been implicated in schizophrenia, bipolar disorder, and ...
Brunwasser, Samuel J +6 more
core +2 more sources
Effect of boxing exergame addition on brain-derived neurotrophic factor of elderly women [PDF]
Romanian Journal of NeurologyBackground and objectives. The elderly population is growing rapidly. The aging process will result in the decline of cognitive functions. The frequency of cognitive impairment is higher in women than in men, resulting in a greater risk of decreased ...
Nadia Rizki Rahmawati +3 more
doaj +1 more source
The pharmacological perturbation of brain zinc impairs BDNF-related signaling and the cognitive performances of young mice. [PDF]
, 2018 Zinc (Zn2+) is a pleiotropic modulator of the neuronal and brain activity. The disruption of intraneuronal Zn2+ levels triggers neurotoxic processes and affects neuronal functioning.
Bomba, Manuela +13 more
core +3 more sources
Neuroprotective effects of physical exercise: Implications in health and disease [PDF]
Romanian Medical Journal, 2021 Physical exercises have long been linked to numerous health improvements, ranging from cardiovascular to psychiatric. In this review, we take a closer look on its anatomical, physiological and chemical effects on the brain.
Sebastian Romeo Pintilie +10 more
doaj +1 more source
Annals of Indian Academy of Neurology, 2020 Objective: Despite advances made in the treatment of ischemic stroke, it still remains one of the leading causes of mortality and disability worldwide.
Adina Hutanu +4 more
doaj +1 more source
Modulation of neurotrophic signaling pathways by polyphenols [PDF]
, 2015 Polyphenols are an important class of phytochemicals, and several lines of evidence have demonstrated their beneficial effects in the context of a number of pathologies including neurodegenerative disorders such as Alzheimer's and Parkinson's disease. In
Firuzi, Omidreza +3 more
core +1 more source
Nerve growth factor, brain-derived neurotrophic factor, and the chronobiology of mood: a new insight into the "neurotrophic hypothesis" [PDF]
, 2015 The light information pathways and their relationship with the body rhythms have generated a new insight into the neurobiology and the neurobehavioral sciences, as well as into the clinical approaches to human diseases associated with disruption of ...
IANNITELLI, ANGELA +2 more
core +2 more sources
The effect of morphine upon DNA methylation in ten regions of the rat brain
Epigenetics, 2017 Morphine is one of the most effective analgesics in medicine. However, its use is associated with the development of tolerance and dependence. Recent studies demonstrating epigenetic changes in the brain after exposure to opiates have provided insight ...
Timothy M. Barrow +7 more
doaj +1 more source