Results 61 to 70 of about 686,893 (389)

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

An improved encapsulation protocol for regrowth and conservation of four ornamental species

open access: yesActa Societatis Botanicorum Poloniae, 2017
The encapsulation technology, initially developed for clonal propagation through the production of synthetic seeds with somatic embryos, is currently proposed for use with non-embryogenic explants, such as buds and nodal segments (unipolar propagules ...
Carla Benelli   +2 more
doaj   +1 more source

Detection of HLA Antibodies in Organ Transplant Recipients – Triumphs and Challenges of the Solid Phase Bead Assay

open access: yesFrontiers in Immunology, 2016
This review outlines the development of human leukocyte antigen (HLA) antibody detection assays and their use in organ transplantation in both antibody screening and crossmatching. The development of sensitive solid phase assays such as the enzyme-linked
B. Tait
semanticscholar   +1 more source

Issue 65, Autumn 2014 [PDF]

open access: yes, 2014
International Conference: Baltic Amber Across Time and Borders, by Karlis Karklins.https://surface.syr.edu/the_bead_forum/1005/thumbnail ...
Society of Bead Researchers
core   +1 more source

Flow in a double-film-fed fluid bead between contra-rotating rolls, Part 2: bead break and flooding [PDF]

open access: yes, 2001
Two-dimensional flow is considered in a fluid bead located in the gap between a pair of contra-rotating cylinders and bounded by two curved menisci. The stability of such bead flows with two inlet films, and hence no contact line, are analysed as the ...
Gostling, M.J.   +2 more
core   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Testing Roman Glass in the Flame

open access: yesEXARC Journal, 2023
Glass made during the Romano British period was recycled throughout the Late Roman and Early Medieval periods. Studies have shown that British beadmakers of the fifth and early sixth centuries AD made a large proportion of their beads using Roman period ...
Sue Heaser
doaj  

To bead or not to bead? Lens-specific intermediate filaments revisited

open access: yesJournal of Cell Science, 1997
ABSTRACT For nearly three decades cytoplasmic intermediate filaments (IFs) have been described as 10 nm thick, unbranched ropes radiating from the cell nucleus and extending to the plasma membrane. This stereotype is now being challenged by the discovery and molecular characterization of the beaded filaments (BFs), a novel class of IFs ...
Georgatos, S. D.   +3 more
openaire   +4 more sources

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

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