Results 121 to 130 of about 614,405 (309)
Chemical and Technological Aspects of Magnetic Particles for Cancer Liquid Biopsy Applications
ChemistryOpenRecent progress in molecular diagnostics has been strongly influenced by advances in magnetic bead (MB) chemistry. Synthetic strategies for MB fabrication play a critical role in defining their size, physicochemical properties, and nano‐ or microscale ...
Beatriz Naranjo‐Martínez +9 more
doaj +1 more source
Astrocyte heterogeneity in brain metastases
Molecular Oncology, EarlyView.Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
Merovingian Beads on the Lower Rhine [PDF]
This paper presents a classification for beads of the Merovingian period (ca. A.D. 450-750) in the Lower Rhine region of Germany. Strings of beads recovered from graves are ordered by a seriation (correspondence analysis) which results in an ethnic ...
Bridger, C.J., Siegmund, Frank
core +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Glass and Lapidary Beads at Jamestown, Virginia: An Updated Assessment [PDF]
, 2019 An updated assessment of the trade beads in the Jamestown collection has long been overdue since Heather Lapham’s 1998 study. The size and variation of the collection has expanded to include nearly 4,000 glass beads representing over 100 Kidd and Kidd ...
Derry, Emma
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Imitation Amber Beads of Phenolic Resin from the African Trade [PDF]
, 2016 Examination of contemporary beads with African provenance reveals large quantities of imitation amber beads made of phenol-formaldehyde thermosetting resins (PFs).
Falabella, Rosanna
core +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source