Results 101 to 110 of about 994,111 (289)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Free-Radical Reaction of Iron(II) Dichloroclathrochelate with 1,3-Dioxolane Radical Derivative: Synthesis and Structure of Macrobicyclic tris-Dioximate Bearing 1,3-Dioxolan-2-yl Ribbed Substituent [PDF]

, 2015
Mikhail A. Vershinin, Alexey B. Burdukov, Н. В. Первухина, Ilia V. Eltsov, Yan Z. Voloshin   +4 more
openalex   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Friction power loss in ball bearings: Correlation with bearing skidding and cage motion stability

Friction
This study introduces a prediction method for bearing friction power loss, focusing on the interplay of bearing skidding and cage motion stability on the tribological properties of ball bearings.
Mingkai Wang, Linbo Zhu, Kim Tiow Ooi, Haizhen Li, Ke Yan, Jun Hong   +5 more
doaj   +1 more source

Study on disc cutting of rock (5th Report). External Load Imposed on a Disc Cutter and Reaction Force Excerted at Bearing Assemblies.

, 1994
Fangming Gong, Kazuhiko Sato, Hideaki Asai   +2 more
openalex   +2 more sources

A large osteoderm-bearing rib from the Upper Triassic Kössen Formation (Norian/Rhaetian) of eastern Switzerland [PDF]

, 2022
Torsten M. Scheyer, Urs Oberli, Nicole Klein, Heinz Furrer   +3 more
openalex   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Measurement of Oil-Film Thickness and Observation of Oil Distribution in High-Speed Deep-Groove Ball Bearings

Tribology Online
High-speed deep-groove ball bearings for the eAxle of electric vehicles must adapt to higher rotational speed conditions, because eAxle motor speed increases to downsize the unit.
Mamoru Tohyama, Yasuhiro Ohmiya, Michiru Hirose, Hiroki Matsuyama, Takuya Toda, Kenichi Hasegawa, Takaaki Onizuka, Hideaki Sato, Masahiro Yokoi, Norikazu Sato   +9 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Pharmacokinetics of Re-188-nanodiamonds complex in mice bearing experimental Ehrlich carcinoma [PDF]

, 2017
В. М. Петриев, В. К. Тищенко, Alesya Mikhailovskaya, A.G. Konoplyannikov   +3 more
openalex   +1 more source