Results 111 to 120 of about 3,237,410 (336)
Advanced bearing study. Part 2: Bearing tests [PDF]
Tests of ball bearings of various material combinations in liquid ...
Comolli, C. R. +2 more
core +1 more source
Preparation of Authigenic Pyrite from Methane-bearing Sediments for <em>In Situ</em> Sulfur Isotope Analysis Using SIMS [PDF]
, 2017 Zhiyong Lin +7 more
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Rolling Contact Fatigue Behaviors of High Carbon Bainitic Bearing Steel [PDF]
, 2017 Chunlei Zheng
openalex +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
LubricantsCarbon quantum dots (CQDs) have already demonstrated their utility as lubricant additives, and non-contact temperature sensing based on CQDs offers considerable potential for condition monitoring in mechanical, electrical, and other fields, as well as ...
Jiannan Sun +5 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Intelligent Design Method for Thermal Conductivity Topology Based on a Deep Generative Network
Chinese Journal of Mechanical EngineeringHeat dissipation performance is critical to the design of high-end equipment, such as integrated chips and high-precision machine tools. Owing to the advantages of artificial intelligence in solving complex tasks involving a large number of variables ...
Qiyin Lin +7 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source