Results 91 to 100 of about 1,167,102 (307)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Damping capacity of a sealed squeeze film bearing [PDF]
The advantages of incorporating an open-ended or weakly-sealed squeeze-film bearing in a flexible support structure simulating an aero-engine assembly were examined.
Dede, M. M., Dogan, M., Holmes, R.
core +1 more source
Analisis Hasil Pengujian Sondir untuk Mengetahui Peningkatan Kekuatan Tanah Sangat Lunak di Lokasi Gate House dalam Pekerjaan “Grouting At Semarang Pumping Station & Retarding Pond” [PDF]
, 2013 The water building structure at the mouth of the Semarang river as a flood prevention building in Panggung Lor village is a high settlement risk building structure. This is caused by lithological estuary region consisting predominantly of fine clay-sized
Wibowo, H. T. (Hendry)
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Peningkatan Daya Dukung Tanah Urugan dengan Metode Grouting di Smk Teuku Umar Semarang, Jawa Tengah [PDF]
, 2013 It is very important to note in bearing capacity of soil in development of multi-storey buildings. There are somegeotechnical investigation can do to determine the value of bearing capacity of soil.
Manalu, A. M. (Agnes)
core
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Computer program for flat sector thrust bearing performance [PDF]
A versatile computer program is presented which achieves a rapid, numerical solution of the Reynolds equation for a flat sector thrust pad bearing with either compressible or liquid lubricants.
Etsion, I., Presler, A. F.
core +1 more source
Flexural behaviour of plain concrete prism strengthened by textile fine grained mortar [PDF]
, 2018 This paper presents a flexural strength study of concrete incorporated with textile fine grained mortar (TFGM) as a strengthening laminate. TFGM is a combination of fine grained mortar (FGM) with alkali resistant glass fabric (AR glass).
A. Khalid, Nur Hafizah +6 more
core +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source