Results 91 to 100 of about 1,605,223 (291)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Вестник Донского государственного технического университета, 2018 A method of calculation of the thrust plain bearing with adapted profile of the bearing capacity, providing the increased bearing capacity of the bearing, working on the stratified two-layer lubrication in the presence of the porous layer on the surface ...
K.S. AKHVERDIEV +3 more
doaj
Effect of Oil Film Parameter on Vibration Acceleration and Electrical Pitting of Small Ball Bearing
Tribology Online, 2012 The authors have studied the current density and voltage at which electrical pitting occurs in a small ball bearing. Some current-applying bearing tests in previous studies showed an interesting tendency for the vibration of bearings to increase when ...
Shoji Noguchi +2 more
doaj +1 more source
Vibration transmission through rolling element bearings in geared rotor system, part 1 [PDF]
A mathematical model is proposed to examine the vibration transmission through rolling element bearings in geared rotor systems. Current bearing models, based on either ideal boundary conditions for the shaft or purely translational stiffness element ...
Lim, Teik Chin, Singh, Rajendra
core +1 more source
Small-scale hero: massive-star enrichment in the Hercules dwarf spheroidal
, 2012 Dwarf spheroidal galaxies are often conjectured to be the sites of the first stars. The best current contenders for finding the chemical imprints from the enrichment by those massive objects are the "ultrafaint dwarfs" (UFDs).
Feltzing, Sofia +2 more
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
A magnetic bearing based on eddy-current repulsion [PDF]
This paper describes a new type of electromagnetic bearing, called the Eddy-Current Bearing, which works by repulsion between fixed AC-electromagnets and a conducting rotor.
Nikolajsen, J. L.
core +1 more source
Apparatus and method for inspecting a bearing ball [PDF]
, 1985 A method and apparatus for inspecting the surface of a ball bearing is disclosed which includes a base having a high friction non-abrasive base scanning surface. A holding device includes a cone-shaped cup recess in which a ball element is received.
Bankston, B. F.
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Performance of PTFE-lined composite journal bearings [PDF]
Plain cylindrical journal bearings consisting of aramid fiber reinforced epoxy outer shells and glass fiber reinforced PTFE lubricating liners were evaluated. All materials in these bearings are electrically nonconductive; thus eliminating the problem of
Sliney, H. E., Williams, F. J.
core +1 more source