Results 51 to 60 of about 1,609,794 (313)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
EnergiesThe present paper deals with a review on bearing currents in electrical machines, with major emphasis on mechanisms, impacts, and mitigation strategies.
Tianyi Pei +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Chengshi guidao jiaotong yanjiuObjective Most urban rail transit trains use PWM (pulse width modulation) variable frequency drive system, which often leads to bearing corrosion problems due to the excessive bearing voltage and bearing current during operation.
CHEN Zhi +5 more
doaj +1 more source
Nihon Kikai Gakkai ronbunshu, 2019 Eddy current method which is uninfluenced by oil film rupture or viscosity change was employed as a simple in-situ estimation method of bearing load acting on deep groove ball bearing operating under low rotational speed.
Akitoshi TAKEUCHI
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Novel Bearing Current Suppression Approach in Doubly-Fed Induction Generators
IEEE Access, 2019 Doubly-fed induction generators (DFIGs) are widely used in the wind power generation systems. However, due to the use of the power electronic devices, such as insulated gate bipolar transistor (IGBT), it is inevitable to generate a non-zero common mode ...
Ruifang Liu +3 more
doaj +1 more source
, 2012 Partial explanations are everywhere. That is, explanations citing causes that explain some but not all of an effect are ubiquitous across science, and these in turn rely on the notion of degree of explanation.
A. Garfinkel +29 more
core +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source