Results 111 to 120 of about 250,541 (308)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Predictors of Dissatisfaction After Polydioxanone Thread Lift: A Multicenter Retrospective Analysis

Plastic and Reconstructive Surgery, Global Open
Background:. Polydioxanone (PDO) thread lift is a widely used technique for minimally invasive facial rejuvenation. Although the technical outcomes and complications are well-documented, postoperative dissatisfaction remains underexplored, particularly ...
Kohki Okumura, MD, Takahiko Tamura, MD, PhD, Yusuke Funakoshi, MD, PhD, Hiroo Teranishi, MD   +3 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Productivity or Discrimination? Beauty and the Exams [PDF]

Do good looks make people more productive? An impact of looks on earnings has been found in the empirical literature: plain people earn less than average-looking people who earn less than the good-looking.
Giam Pietro Cipriani, Angelo Zago
core  

Beauty and Professional Success: A Meta-Analysis

Common wisdom suggests that beauty helps in the labor market. We show that two factors combine to explain away the mean beauty premium reported in the literature. First, correcting for publication bias reduces the premium by at least a third.
Kseniya Bortnikova, Tomas Havranek, Zuzana Irsova   +2 more
core   +1 more source

Doctoring Beauty. Beauty and Medicine in the Middle Ages and Early Modern Europe

, 2023
Beauty cultures have a remarkable history as the practices, texts, and artefacts involved have circulated and transformed through time and space. The collective lecture traces the aesthetic praxeology of European beauty cultures from antiquity to the ...
Antenhofer, Christina, Calà, Irene, Sammern, Romana, Seidl, Katharina, Cabré, Montserrat, McCall, Timothy   +5 more
core  

Multicenter Review of More Than 110,000 Facial Thread Lifting Cases From a Cosmetic Surgery Group

Plastic and Reconstructive Surgery, Global Open
Background:. Thread lifting is a minimally invasive aesthetic procedure that has gained popularity for facial rejuvenation. However, large-scale multicenter studies assessing trends, patient characteristics, and procedural variations are limited.
Takahiko Tamura, MD, PhD, Kohki Okumura, MD, Yusuke Funakoshi, MD, PhD, Hiroo Teranishi, MD   +3 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

The Key to Healthy and Radiant Skin with Balanced Nutrition

Magna Medika
Background: Skin and appearance are essential indicators of overall health and age. Nutrition plays a crucial role in supporting the skin's structure, function, and resistance to environmental stressors, highlighting the importance of a balanced diet in ...
Nurul Safitri, Berliana Manik Ayu Cahyaningtyas, Vika Sugianto Putri, Locita Dewani, Eti Nugraheni, Arifa Nayla Nugrahanti, Mersita Septianti Saputri, Eny Widhia Agustin   +7 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source