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IMPLEMENTASI FAIR TRADE OLEH L'OCCITANE GROUP DALAM UPAYA PEMBERDAYAAN LINGKUNGAN DAN KOMUNITAS BERKELANJUTAN MELALUI INDUSTRI KECANTIKAN [PDF]

open access: yes
The intersection of capitalism and the beauty industry has given rise to a concept known as beauty capitalism. Globalization has propelled capitalism in the beauty industry to become massive and expansive, resulting in exploitative impacts on the ...
Jasmine, Queen Salsabila
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Hadrons with Charm and Beauty

open access: yes, 1994
By combining potential models and QCD spectral sum rules (QSSR), we discuss the spectroscopy of the $(b\bar c)$ mesons and of the $(bcq)$, $(ccq)$ and $(bbq)$ baryons (${q}\equiv {d}$ or $s$), the decay constant and the (semi)leptonic decay modes of the $
A. Martin   +51 more
core   +3 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Impact of Beauty and Charm H1-ZEUS Combined Measurements on PDFs and Determination of the Strong Coupling

open access: yes, 2017
In this QCD analysis, we investigate the impact of recent measurements of heavy-flavor charm and beauty cross sections data sets on the simultaneous determination of Parton Distribution Functions (PDFs) and the strong coupling, $\alpha_s(M^2_Z)$.
Khorramian, A., Vafaee, A.
core   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Impact of skin sensitivity mechanisms on sebum secretion: Management strategies for oily sensitive skin

open access: yesJournal of Dermatologic Science and Cosmetic Technology
Recent epidemiological surveys based on Baumann's classification have revealed a notable rise in the prevalence of oily sensitive skin. The development of oily sensitive skin is primarily linked to the abnormal function of sebaceous glands.
Yijie Du   +7 more
doaj   +1 more source

Beauty and the Beastly Prime Minister [PDF]

open access: yes, 2014
This essay examines the so-called “turn to beauty” in British fiction since the 1990s as a response to the political and social consequences of Thatcherism. Focusing primarily on four texts—Jonathan Coe’s What a Carve Up! (1994), Julian Barnes’s England,
Su, John J.
core   +1 more source

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