Results 91 to 100 of about 564,247 (303)

The aestheticization of wisdom and homeliness as a distinctive feature of the intellectual culture of Japan

open access: yesЯпонские исследования
The article reveals the distinctive features of Japanese aesthetic culture and the conceptual foundations of its main aesthetic categories (mono no aware, yugen, wabisabi, ma).
Krinitskaya Yulia O.
doaj   +1 more source

Beauty Before the Eyes of Others [PDF]

open access: yes, 2016
This paper pursues the philosophical significance of a relatively unexplored point of Platonic aesthetics: the social dimension of beauty. The social dimension of beauty resides in its conceptual connection to shame and ...
Fine, Jonathan
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Mirror, Mirror on the Wall, Who Is the of All? Racial Biases in Social Media Beauty Filters

open access: yesSocial Media + Society
Digital beauty filters are pervasive in social media platforms. Despite their popularity and relevance in the selfies culture, there is little research on their characteristics and potential biases.
Piera Riccio   +3 more
doaj   +1 more source

Breaking the Mold: Four Asian American women define beauty, detail identity, and deconstruct stereotypes [PDF]

open access: yes, 2014
The experiences of four women reveal how notions of outer beauty touch ideas of personal ethnic identity, racism, media-imposed pressure, and social stereotypes; shaping the lives of Chinese, Chinese American, and Asian American ...
Ginwala, Allison
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Pusat Kebudayaan Jepang di Pekanbaru dengan Penerapan Prinsip Desain Kenzo Tange [PDF]

open access: yes, 2017
Culture is a comprehensive lifestyle that is complex, abstract and broad. Along with the globalization, many cultures from other countries are entering and growing in Indonesia.
Aldy, P. (Pedia)   +2 more
core  

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

Making a Transnational Design History in East Asia: Yen Shuilong’s Craft-Design Movement [PDF]

open access: yes, 2013
Yen Shuilong (1903-97) was born in Taiwan within the ‘Japanese Empire’ but his live is dominated by what we would now call transnational activities. During the fifteen years since his death, there have been a number of retrospective exhibitions on him ...
Kikuchi, Yuko
core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

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