Results 81 to 90 of about 4,015,063 (294)
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
A Review of ‘Beauty’ by Bri Lee
, 2020 [Extract] After investing so much time in the solitary act of writing, a book tour must feel like a daunting prospect. The related pressures of photoshoots, school visits, and the public gaze figure prominently in Bri Lee’s sophomore work Beauty.
Burrows, Lianda
core +1 more source
BEAUTIFUL, SENSE OF BEAUTY AND ELEMENTS OF BEAUTY IN TURKISH “MÂNİ”
Zeitschrift für die Welt der Türken, 2014 This study underlines the “mâni” which represents anonymous folk literature reflecting Turkish cultural life. Turkish nation’s sense of beautiful and beauty, the elements of beauty which belong to beauty/beloved have been studied with reference to ...
Bülent Kahraman Çolakoğlu
doaj
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Success: talent, intelligence or beauty ? [PDF]
We analyze the Celebrity 100 annual list of the world’s most “powerful celebrities” compiled and published by Forbes Magazine. The lists provide an interesting collection of people, that includes their earnings, and the perception of citizens concerning ...
GINSBURGH, Victor, GERGAUD, Olivier
core
Beauty is in the Eye of the Cultural Beholder
, 2020 Is face beauty universally perceived from a common basis of objectively definable face features, or is it irreducibly subjective and in the idiosyncratic eye of the cultural, or even individual beholder? We addressed this longstanding debate by objectively modelling the face beauty preferences of 80 individual male participants across Western European (
Jiayu Zhan +6 more
openaire +2 more sources
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Level 1 beauty culture; Level 2 beauty culture; Level III beauty culture
, 1980 Course outline for beauty culture - Pre vocational, levels 1, 2, and 3Course outline for beauty culture : level 1 pre vocational -- Course outline for beauty culture : level 2 pre vocational -- Course outline for beauty culture : level 3 pre ...
core
The measure of existence of a quantum world and the Sleeping Beauty Problem [PDF]
, 2013 An attempt to resolve the controversy regarding the solution of the Sleeping Beauty Problem in the framework of the Many-Worlds Interpretation led to a new controversy regarding the Quantum Sleeping Beauty Problem.
Vaidman, Lev +2 more
core