Results 71 to 80 of about 18,246 (255)
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Lebenswelt: Aesthetics and Philosophy of Experience, 2018 The article: 1. analyzes the Anglo-American philosophical works which, in the last thirty years, focus on the notion of beauty by making reference to Kant’s work (in particular, Beauty restored by Mary Mothersill, Only a promise of happiness: the place ...
Simona Chiodo
doaj +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
BEAUTY MYTH AND ITS EFFECTS SEEN IN THE MISS CONGENIALITY (2000) MOVIE
FrasaThis study examines the beauty myths depicted by female characters in the film Miss Congeniality (2000), including Gracie, Cheryl, Leslie, and Mary. The film follows Gracie, a female FBI agent who goes undercover as a beauty pageant entrant, forcing her
Dita Ulfiani, Riana Permatasari
doaj +1 more source
, 2022 The beauty industry has been booming in the last few years, generating immense profits as it now translates into an Internet global beauty culture in its own right that finally made room for women of color. As research barely mentions African women and their diasporas, this study aims to critically analyze the dynamic of this North American-dominated ...
openaire +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo +7 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang +9 more
wiley +1 more source
Applied SciencesWhole-body cryotherapy (WBC) is a widely used method that exposes the body to extremely low temperatures to induce physiological responses. While its analgesic, anti-inflammatory, and anti-edema effects are well-documented, the effects of WBC on the skin
Adrianna Dzidek +6 more
doaj +1 more source