Results 71 to 80 of about 561,283 (308)
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Java in Puma (Pop Up Map) [PDF]
, 2013 Indonesia is a country rich islands cultural diversity. This leads to a lot of other nations came to Indonesia to enjoy the beauty of Indonesian culture and learning.
Soedarmodjo, T. P. (Theo)
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Misleading Aesthetic Norms of Beauty: Perceptual Sexism in Elite Women's Sports [PDF]
, 2016 The history of gender challenges faced by women in elite sports is fraught with controversy and injustice. These athletes' unique physical beauty creates what appears to be a paradox yet is, in fact, scientifically predictable.
Weiser, Edward B. +1 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The making of a local queen in an international transsexual beauty contest
, 2005 This paper will examine the intricacies in beauty contests and the tensions brought about by the negotiation of a local, authentic culture in the face of Western-derived notions of beauty and femininity.
AsiaPacificQueer Network +1 more
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Beauty and the Beastly Prime Minister [PDF]
, 2014 This essay examines the so-called “turn to beauty” in British fiction since the 1990s as a response to the political and social consequences of Thatcherism. Focusing primarily on four texts—Jonathan Coe’s What a Carve Up! (1994), Julian Barnes’s England,
Su, John J.
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Access Magazine, March 2016 [PDF]
, 2016 https://scholarworks.sjsu.edu/accessmagazine/1014/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source