Results 91 to 100 of about 383,509 (342)
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Beauty Salons are Key Potential Sources of Disease Spread
Infection and Drug Resistance, 2021 Najwa Menwer Alharbi, Hanan Mohammed Alhashim King Abdelaziz University, Science College, Biology Department, Jeddah, Saudi ArabiaCorrespondence: Najwa Menwer AlharbiKing Abdelaziz University, Science College, Biology Department, P.O. Box: 80200, Jeddah,
Alharbi NM, Alhashim HM
doaj
Meaning in Life and the Metaphysics of Value [PDF]
, 2017 According to subjectivist views about a meaningful life, one's life is meaningful in virtue of desire satisfaction or feelings of fulfilment. Standard counterexamples consist of satisfaction found through trivial or immoral tasks.
Evers, Daan
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Female body perception: social norms, criticism, and the impact of weight perception
International Journal of Qualitative Studies on Health & Well-BeingPurpose This study aims to explore the multifaceted nature of women's body perception and the personal and social factors that influence it. The research investigates how societal expectations, health concerns, and self-perception intersect in shaping ...
Reşat Sadık, Gizem Nur Yılmaz
doaj +1 more source
CrossingsThe socio-cultural construction of beauty simultaneously generates a normative understanding of unattractiveness as well, since these properties exist in binary within popular perceptions.
Ahmed Abdullah Bin Farooqi Rayhan
doaj +1 more source
Slathered, Zapped, Nipped, and Tucked: An Ethical Analysis of Cosmetic Dermatology [PDF]
, 2017 It has become common practice for dermatologists to offer cosmetic enhancing products and procedures and to do so alongside the medically required services offered (e.g., annual skin checks, treatment of rashes, removal of pre-cancerous moles, etc.).
Lowe, Barbara
core +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
, 2014 ***TRIGGER WARNING: Eating Disorders*** I don’t care what anyone says—being a woman is hard. Being a young woman has its own set of complications–we experience a lot of pressure to look a certain way, to act a certain way, to have a specific friend group;
Lauro, Alison P.
core