Results 71 to 80 of about 383,509 (342)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Beauty class and the practice of beautification among lower middle-class young women

open access: yesDigital Press Social Sciences and Humanities, 2018
Beauty class is a place for a woman to share experiences in applying makeup. The participants in the beauty class obtain tips and trick or some specific ways of applying makeup. The participants in this class can directly practice the knowledge on how to
Ambarwati, Ninik Tri
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

“Best Before”: On Women, Ageism, and Mental Health

open access: yesMental Health
Introduction: Our world has changed over the last decades, and one of the dramatic changes has been the increase in human life expectancy. Due to important life-saving breakthroughs, the current life expectancy for the world in 2024 is 73.33 years; and ...
Danylova Tetiana   +6 more
doaj   +1 more source

Performer pour durer

open access: yesRecherches Sociologiques et Anthropologiques, 2020
Choosing to adopt an approach that is both critical and based on the discourses of actors, producers and directors of gay pornographic films, this article seeks to show that the injunctions of pornographic work and the logics of professionalisation ...
Tanguy Dufournet
doaj   +1 more source

Mirror, Mirror on the Wall, Who\u27s the Thinnest of Them All? [PDF]

open access: yes, 2012
Societal standards of feminine beauty are presented in all forms of popular culture, thus bombarding women with images that portray what our society considers to be the “ideal body type.” These images, as seen on the cover of magazines, in popular films ...
O\u27Brien, Ann Marie
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Aesthetic Transcendence: Fashion's Evolution, Philosophical Reflections, and Societal Impact

open access: yesJournal of Current Social and Political Issues
This research paper explores the evolution of fashion from its utilitarian origins over 170,000 years ago to its contemporary role as a symbol of cultural expression and individual identity. Tracing the historical trajectory through ancient civilizations,
Ankita Sharma
doaj   +1 more source

Occidentalisation of Beauty Standards: Eurocentrism in Asia

open access: yes, 2020
Beauty standards have long been set in place within society. However the origins of such beauty standards are a topic of discussion and frequently up for debate. Our paper takes a look into the origins, impacts, and implications of beauty standards within various regions of Asia, including Central Asian, South Asia, East Asia, and the Middle East and ...
Chen, Toby   +4 more
openaire   +2 more sources

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

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