Results 31 to 40 of about 11,761 (260)

Transtornos alimentares: o papel dos aspectos culturais no mundo contemporâneo Transtornos alimentarios: el papel de los aspectos culturales en el mundo contemporáneo Eating disorders: the role of cultural aspects in the contemporary world

Psicologia em Estudo, 2010
Os transtornos alimentares são patologias caracterizadas primordialmente pelo medo mórbido de engordar. Vários são os fatores envolvidos tanto na etiologia quanto na manutenção e na gravidade dessas doenças, principalmente fatores individuais, familiares
Leticia Langlois Oliveira, Claúdio Simon Hutz   +1 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Women’s Body Objectification Under Capitalist Ideas of Beauty in Japanese Society Portrayed in The Novel Breasts and Eggs by Mieko Kawakami

Humanis
Capitalistic ideas of beauty in Japanese society are found in how beauty is perceived as social demand and necessity. This study attempts to reveal how the perception of women’s body and beauty in Breasts and Eggs is heavily influenced by the patriarchal
Yoshinta Nur Prihatina, Imas Istiani
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The dual nature of paraphenylenediamine: beauty product or suicidal weapon?

Journal of the Pakistan Medical Association
Dear editor, Paraphenylenediamine (PPD), referred to as "Black Stone" in Arabic-speaking regions and "Kala Pathar" in South Asia, is a derivative of para-nitroaniline that is produced industrially synthesised(1).
Maheen Sheraz, Rabia Amir, Laiba Amir Shaikh   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The healthy eating movement on social media and its psychological effects on body image

Frontiers in Nutrition
IntroductionThe present study aims to investigate the relationship between social-media pressure, the tendency to internalize standards of beauty and attractiveness associated with thin bodies, which subsequently leads to distortion of body shape ...
Alina Zaharia, Iulia Gonța
doaj   +1 more source

Senses of body image in adolescents in elementary school

Revista de Saúde Pública, 2014
OBJECTIVE : To comprehend the perception of body image in adolescence. METHODS : A qualitative study was conducted with eight focus groups with 96 students of both sexes attending four public elementary school institutions in the city of Rio de ...
Maria Lídia de Abreu Silva, Stella Regina Taquette, Evandro Silva Freire Coutinho   +2 more
doaj   +1 more source