Results 51 to 60 of about 380,446 (306)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Beauty in Black and White? Race, Beauty, and the 1926 Fox Film Photogenic Beauty Contest in Brazil

open access: yesLatin American Research Review, 2019
In 1926, the Fox Film Corporation held a “Masculine and Feminine Photogenic Beauty Contest” to find Hollywood’s newest “Latin” star in Brazil and other countries. North American film representatives asked for contestants who were “white with Latin blood.”
Lena Oak Suk
doaj   +1 more source

Perceived quality of full HD video - subjective quality assessment [PDF]

open access: yes, 2016
In recent years, an interest in multimedia services has become a global trend and this trend is still rising. The video quality is a very significant part from the bundle of multimedia services, which leads to a requirement for quality assessment in the ...
Bienik, Juraj   +3 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

The Beauty Ideal

open access: yesColumbia Social Work Review, 2019
Black women are particularly vulnerable to the effects of European standards of beauty, because these standards emphasize skin colors and hair types that exclude many black women, especially those of darker skin.
Susan L. Bryant
doaj  

Beauty class and the practice of beautification among lower middle-class young women

open access: yesDigital Press Social Sciences and Humanities, 2018
Beauty class is a place for a woman to share experiences in applying makeup. The participants in the beauty class obtain tips and trick or some specific ways of applying makeup. The participants in this class can directly practice the knowledge on how to
Ambarwati, Ninik Tri
doaj   +1 more source

Diploma qualifications monitoring: findings from the scrutiny of level 2 and level 3 diploma constituent qualifications in 2010 [PDF]

open access: yes, 2011
In 2010, the Office of Qualifications and Examinations Regulation (Ofqual) monitored three new specifications in principal learning: Edexcel level 3 in Construction and the Built Environment; OCR level 3 in Information Technology; and VTCT level 2 in ...

core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Performer pour durer

open access: yesRecherches Sociologiques et Anthropologiques, 2020
Choosing to adopt an approach that is both critical and based on the discourses of actors, producers and directors of gay pornographic films, this article seeks to show that the injunctions of pornographic work and the logics of professionalisation ...
Tanguy Dufournet
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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