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VCP/p97 regulates Beclin-1-dependent autophagy initiation [PDF]

open access: yesNature Chemical Biology, 2021
Autophagy is an essential cellular process that removes harmful protein species, and autophagy upregulation may be able to protect against neurodegeneration and various pathogens. Here, we have identified the essential protein VCP/p97 as a novel regulator of autophagosome biogenesis, where VCP regulates autophagy induction in two ways, both dependent ...
S. M. Hill   +6 more
semanticscholar   +3 more sources

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