Results 41 to 50 of about 7,475 (265)

The Northern Widow Spider, Latrodectus Variolus (Araneae: Theridiiae), in Michigan [PDF]

open access: yes, 2017
Until recently the species of widow spider occurring in Michigan was considered a variant of the black widow, Latrodectus mactans (Fabricius). Levi (1959) summarized and revised the worldwide genus Latrodectus, placing the southern areas of Illinois ...
Wilson, Louis F
core   +3 more sources

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang   +7 more
wiley   +1 more source

Specific immunotherapy in Albanian patients with anaphylaxis to hymenoptera venoms [PDF]

open access: yes, 2002
Background: Severe allergic reactions during rush-specific immunotherapy (Rush-SIT) may occur in the treatment of hymenoptera sting allergy. The objective of the present study was to examine the characteristics of allergic reactions during Rush-SIT in a ...
Dinh, Q. Thai   +6 more
core  

Friends or Foes? Emerging Impacts of Biological Toxins [PDF]

open access: yes, 2019
Toxins are substances produced from biological sources (e.g., animal, plants, microorganisms) that have deleterious effects on a living organism. Despite the obvious health concerns of being exposed to toxins, they are having substantial positive impacts
Casewell, N.R.   +6 more
core   +6 more sources

An ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism

open access: yesAdvanced Science, EarlyView.
The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty   +21 more
wiley   +1 more source

Ecology and evolution of pyrazines in insects

open access: yesBiological Reviews, EarlyView.
ABSTRACT Chemical communication is the oldest and most widespread form of signalling among and within organisms. Among the many compounds involved in such communication, pyrazines – nitrogen‐containing heterocyclic molecules – are especially intriguing due to their widespread occurrence across the tree of life, from bacteria and fungi to insects and ...
Zowi Oudendijk   +2 more
wiley   +1 more source

A Novel Hyaluronidase from Brown Spider (Loxosceles intermedia) Venom (Dietrich's Hyaluronidase): From Cloning to Functional Characterization [PDF]

open access: yes, 2013
Loxoscelism is the designation given to clinical symptoms evoked by Loxosceles spider's bites. Clinical manifestations include skin necrosis with gravitational spreading and systemic disturbs. the venom contains several enzymatic toxins.
Chaim, Olga Meiri   +9 more
core   +4 more sources

Developing a Typology of Korean Women Leaders' Resistance to Their Token Status in the Workplace

open access: yesHuman Resource Development Quarterly, EarlyView.
ABSTRACT Despite remarkable economic development in South Korea (Korea), there are only a few women leaders, and they face challenges in the gendered workplace where organizational constraints and traditional values coexist. In a reanalysis of narratives of Korean women leaders (KWLs), using an ideal‐type analysis as a novel qualitative research method,
Yonjoo Cho   +4 more
wiley   +1 more source

Low-level laser therapy decreases local effects induced by myotoxins isolated from Bothrops jararacussu snake venom [PDF]

open access: yes, 2010
The prominent myotoxic effects induced by Bothrops jararacussu crude venom are due, in part, to its polycationic myotoxins, BthTX-I and BthTX-II. Both myotoxins have a phospholipase A2 structure: BthTX-II is an active enzyme Asp-49 PLA2, while BthTX-I is
BARBOSA, AM   +6 more
core   +2 more sources

The effects of royal jelly on human health: A narrative review of clinical studies

open access: yesJSFA reports, EarlyView.
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Goras Georgios   +2 more
wiley   +1 more source

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