Results 121 to 130 of about 212,684 (303)

Blood SOD1 Activity in ALS Patients Receiving Tofersen Treatment

open access: yesAnnals of Neurology, EarlyView.
Objective The antisense oligonucleotide tofersen is the first disease‐modifying drug for SOD1‐related amyotrophic lateral sclerosis (ALS) and was approved because of its ability to reduce SOD1 protein and neurofilament levels. The effect of tofersen on SOD1 activity is unclear but of clinical relevance because homozygous SOD1 mutations, linked to ...
Katharina Goehring   +18 more
wiley   +1 more source

Ueber Blanchard und seine jüngste Luftfahrt zu Leipzig : Zwei Briefe

open access: yes
Autopsie nach Ex. der ULB Sachsen-AnhaltVorlageform des Erscheinungsvermerks: Leipzig, in Kommission bei G. E. Beer, 1787.Frontisp. (Kupferst.
unknown
core   +1 more source

A suitable model of microbial survival curves for beer pasteurization

open access: yes, 2007
Published isothermal inactivation data indicated that beer can undergo under- or over-processing depending on the target log reduction and the shape of the survival curve of a microorganism if traditional first-order model is used.
Buzrul, Sencer
core   +1 more source

Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

open access: yesAdvanced NanoBiomed Research, EarlyView.
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira   +7 more
wiley   +1 more source

Ein Ruthenium(CAAC‐5)‐Olefin‐Metathese‐Katalysator für die Biokonjugation

open access: yesAngewandte Chemie, EarlyView.
Die Instabilität von Rutheniumkatalysatoren in wässrigen Lösungen schränkt die Olefinmetathese in biologischen Medien ein. Es wird über einen Ru(CAAC‐5)‐Komplex berichtet, der unter biologisch relevanten Bedingungen aktiv bleibt und die Biokonjugation mit Proteinen, Peptiden und einem künstlichen Metalloenzym ermöglicht.
Damian Alexander Graf   +4 more
wiley   +1 more source

Can Niche Agriculturalists Take Notes from the Craft Beer Industry? [PDF]

open access: yes
This industry-level case study focuses on the growth cycles of craft brewing, a niche industry. The research case is defined as the craft beer industry evolution including the surrounding institutional and consumer environments.
Woolverton, Andrea E.   +1 more
core  

Women drinking manioc beer

open access: yes, 1969
Women drinking manioc beer, served in bottleneck gourd, inside longhouse.
Jackson, Jean
core  

The Effects of Pasteurization and Beer Type on the Functional Compounds and Flavor Substances in Beer

open access: yes
The study of functional compounds is of great importance for the production of nutrient-rich and flavorful beer. In this study, the effects of the pasteurization process and beer type (lager and ale, draft beer, and ripe beer) on the types and contents ...
Jianghua Li   +4 more
core   +1 more source

A Ruthenium(CAAC‐5) Olefin Metathesis Catalyst for Bioconjugation

open access: yesAngewandte Chemie International Edition, EarlyView.
The aqueous instability of ruthenium catalysts restricts olefin metathesis in biological media. A Ru(CAAC‐5) complex bearing an aniline handle is reported that remains active under biologically relevant conditions and enables bioconjugation to proteins, peptides, and an artificial metalloenzyme, providing a robust platform for olefin metathesis in ...
Damian Alexander Graf   +4 more
wiley   +1 more source

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