Results 171 to 180 of about 297,345 (313)

A Joint Pharmacometric Model of Iohexol and Creatinine Administered through a Meat Meal to Assess GFR and Renal OCT2/MATE Activity

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Accurately assessing glomerular filtration rate (GFR) from plasma creatinine concentrations is challenging in patients with unstable renal function. This study aimed to refine the understanding of creatinine kinetics for more reliable assessments of GFR and net creatinine tubular secretion (nCTS) via OCT2/MATE in humans.
Zhendong Chen   +5 more
wiley   +1 more source

School‐based interventions to improve emotional regulation skills in adolescent students: A systematic review

open access: yesJournal of Adolescence, Volume 94, Issue 8, Page 1051-1067, December 2022., 2022
Abstract Introduction Emotional regulation (ER) is a core variable involved in the onset and maintenance of mental health disorders; therefore, interventions targeting ER in adolescence represent a promising preventive action. The current systematic review provides a synthesis of the evidence on school‐based interventions on ER in adolescent students ...
Laura Pedrini   +3 more
wiley   +1 more source

Impulsivity, peer pressure, and social media usage as predictors of addictive gambling behavior among undergraduates

open access: yesJournal of Indonesian Psychological Science
The increased rate of gambling in our society has become a menace that affects nearly every Nigerian youth, including undergraduates. Studies using different predictors of addictive gambling behavior have produced varying results.
Mojisola S. Ajayi   +2 more
doaj   +1 more source

Current Status and Future Directions in the Development of Digital Therapeutic Interventions for Neurodevelopmental Disorders

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Innovations in digital technologies have emerged digital therapeutics (DTx) as a novel therapeutic intervention. DTx hold potential as novel theragnostics for disorders with broad diagnostic spectra, including neurodevelopmental diseases (NDDs). In this review, we highlight challenging factors in the successful development and deployment of DTx for ...
Hyun‐ju Lee   +11 more
wiley   +1 more source

Metabolism study of 3‐chloromethcathinone (3‐CMC) by dried blood spot (DBS) sampling after controlled administration using a murine model

open access: yesDrug Testing and Analysis, EarlyView.
The metabolism of 3‐chloromethcathinone (3‐CMC) was studied after controlled administration in a murine model using the dried blood spot (DBS) technique for the sampling, storage and purification of blood samples. The metabolite profile of 3‐CMC was studied by LC‐HRMS, while the stability of 3‐CMC and its three identified metabolites was also assessed ...
Serena Mestria   +6 more
wiley   +1 more source

Advancing access to Medicare‐funded mental health treatment during the opioid epidemic: A counselor advocacy analysis

open access: yesJournal of Counseling &Development, Volume 101, Issue 1, Page 15-28, January 2023., 2023
Abstract Although advocacy is a priority for counseling professionals, little is known about counseling advocates’ participation in the legislative advocacy process. Recent legislation to address the opioid crisis allowed counseling advocates to provide public comments to advance counselor inclusion in the Medicare program.
Jordan B. Westcott   +2 more
wiley   +1 more source

Human phase‐I metabolism of three synthetic cannabinoids bearing a cumyl moiety and a cyclobutyl methyl or norbornyl methyl tail: Cumyl‐CBMEGACLONE, Cumyl‐NBMEGACLONE, and Cumyl‐NBMINACA

open access: yesDrug Testing and Analysis, EarlyView.
The human phase‐I metabolism of three SCRAs bearing a cumyl moiety and a CBM or NBM tail, based on LC‐qToF‐MS data of authentic urine specimens. Abstract Synthetic cannabinoid receptor agonists (SCRAs) continue to show high prevalence on the new psychoactive substances drug market.
Arianna Giorgetti   +6 more
wiley   +1 more source

Associations Between Self‐Reported Cocaine Use Patterns and Cocaine and Its Metabolites in Hair: Implications for Clinical and Forensic Practices

open access: yesDrug Testing and Analysis, EarlyView.
This study demonstrates that concentrations of cocaine and its main metabolites in hair reliably predict an individual's actual intensity of cocaine use and effectively differentiate between dependent and non‐dependent users. ABSTRACT In forensic toxicology, it has been debated if hair testing allows an estimation of the intensity of cocaine use—an ...
Simon Grison   +4 more
wiley   +1 more source

Adolescence dropout risk predictors: Family structure, mental health, and self‐esteem

open access: yesJournal of Community Psychology, Volume 51, Issue 1, Page 120-136, January 2023., 2023
Abstract This study investigated the predictive roles of family structure, mental health, and self‐esteem in dropout risk among school‐going adolescents in the Ibadan Municipality of Oyo State, Nigeria. A quantitative research design approach was adopted.
Kehinde Clement Lawrence   +1 more
wiley   +1 more source

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