Results 61 to 70 of about 156,693 (286)

Potential of D-cycloserine in the treatment of behavioral and neuroinflammatory disorders in Parkinson's disease and studies that need to be performed before clinical trials

open access: yesKaohsiung Journal of Medical Sciences, 2012
Hyperactivation of glutamatergic N-methyl-D-aspartate (NMDA) receptors has been implicated in the excitotoxicity and pathophysiology of Parkinson's disease (PD).
Cornelius Rainer Pawlak   +3 more
doaj   +1 more source

Addiction as a Disorder of Self-Control [PDF]

open access: yes, 2018
Impairment of self-control is often said to be a defining feature of addiction. Yet many addicts display what appears to be a considerable amount of control over their drug-oriented actions.
Henden, Edmund
core   +1 more source

Delta Opioid Receptors within the Cortico‐Thalamic Circuitry Underlie Hyperactivity Induced by High‐Dose Morphine

open access: yesAdvanced Science, EarlyView.
Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li   +13 more
wiley   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

open access: yesAdvanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren   +9 more
wiley   +1 more source

Changes of consultation-liaison psychiatry practice in Italian general hospitals: A comparative 20-year multicenter study

open access: yesFrontiers in Psychiatry, 2022
IntroductionConducted under the auspices of the Italian Society of Consultation Liaison Psychiatry (SIPC) the aim of this study was to describe the characteristics of Consultation Liaison Psychiatry (CLP) activity in Italy (SIPC-2—2018) over the past 20 ...
Luigi Zerbinati   +45 more
doaj   +1 more source

Introduction to Behavioral Addictions [PDF]

open access: yesThe American Journal of Drug and Alcohol Abuse, 2010
Several behaviors, besides psychoactive substance ingestion, produce short-term reward that may engender persistent behavior, despite knowledge of adverse consequences, i.e., diminished control over the behavior. These disorders have historically been conceptualized in several ways. One view posits these disorders as lying along an impulsive-compulsive
Jon E, Grant   +3 more
openaire   +2 more sources

Conñerning Theoretical Grounds of Addictive Behavior [PDF]

open access: yes, 2015
статті розкрито актуальність досліджуваного феномену. Дано визначення адиктивної поведінки, розкрито її форми, причини виникнення та фази розвитку. The actuality of research phenomenon is discovered in this article.
Ostapiovska, Tetiana P.   +3 more
core  

The DMHGABA Neurons Play a Crucial Role in The Regulation of Cold‐Induced White Adipose Browning through DMH to LPO Projection

open access: yesAdvanced Science, EarlyView.
GABAergic neurons in the dorsomedial hypothalamus (DMHGABA neurons) act as a key neuronal population controlling cold exposure‐induced white adipose tissue browning. DMHGABA neurons regulate the browning through DMH to the lateral preoptic area (LPO) projection.
Zhijie Su   +14 more
wiley   +1 more source

Types and Forms of Addictive Behavior of Law Enforcement Employees

open access: yesПсихология и право, 2019
The article discusses types and forms of an addictive behavior of law enforcement officers (in terms of employees of internal affairs bodies) in conjunction with individual psychological characteristics.
Chernyshova E.V., Suslova V.R.
doaj   +1 more source

Cortical Glutamate and GABA Changes During Early Abstinence in Alcohol Dependence and Their Associations With Benzodiazepine Medication

open access: yesFrontiers in Psychiatry, 2021
In this report, we present cross-sectional and longitudinal findings from single-voxel MEGA-PRESS MRS of GABA as well as Glu, and Glu + glutamine (Glx) concentrations in the ACC of treatment-seeking alcohol-dependent patients (ADPs) during detoxification
Guoying Wang   +8 more
doaj   +1 more source

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