Results 131 to 140 of about 27,722,235 (281)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Training conditional discriminations with fixed and titrated delayed matching to sample in children [PDF]

, 2011
In a series of experiments, we investigated the effects of delayed matching-to-sample (DMTS) on responding in accordance with stimulus equivalence in children. In Experiment 1, 20 participants were assigned to either 3 s or 6 s DMTS.
Lian, Torunn, Arntzen, Erik
core  

Tracking and Behavior Analysis of Group-Housed Pigs Based on a Multi-Object Tracking Approach

Animals
Smart farming technologies to track and analyze pig behaviors in natural environments are critical for monitoring the health status and welfare of pigs.
Shuqin Tu, Jiaying Du, Yun Liang, Yuefei Cao, Weidian Chen, Deqin Xiao, Qiong Huang   +6 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Grammatical constructions in typical developing children: effects of explicit reinforcement, automatic reinforcement and parity [PDF]

, 2012
This study replicated and extended Wright (2006) and Whitehurst, Ironsmith, and Goldfein (1974) by examining whether preschool aged children would increase their use of passive grammatical voice rather than using the more age-appropriate active ...
Eikeseth, Svein, Østvik, Leni, Klintwall, Lars   +2 more
core  

The history of behavior analysis: Some historiography and a bibliography [PDF]

, 1990
field and methodological issues of historiography pertaining to behavior analysis, bibliography appendedIntroduces the field of historiography (HSG) as it pertains to behavior analysis (BA), and provides a selective bibliography of BA by publication type
Todd, James T., Schneider, Susan M., Morris, Edward K., Midgley, Bryan D.   +3 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Mechanism and contextualism in behavior analysis: Just some observations

, 1993
contemporary contextualism and mechanistic philosophy and relation to behavior analysis, commentary replyResponds to peer commentary on his original article (see record 1993-39723-001) on behavior analysis and mechanism written by D. E. Blackman, R.
Morris, Edward K.
core   +1 more source