Results 101 to 110 of about 10,938,470 (249)

“ Build back the confidence”: qualitative exploration of community experiences with polio vaccination in the Covid-19 context in Cameroon and Ethiopia

BMC Public Health
Background In 2020, as the Global Polio Eradication Initiative worked to address outbreaks of vaccine-derived poliovirus Type 2, particularly in sub-Saharan Africa, the Covid-19 pandemic suspended routine immunization campaigns worldwide.
Lara Lorenzetti, Chaudhary Mohd Parvez Alam, Emily Namey, Claude Monj, Ademe Tsegaye, Nasir Ateeq, Douglas Mbang Massom, Grace McLain, Soterine Tsanga, Ross Mcintosh   +9 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

A Supplement to the President's Budget for Fiscal Year 2011

, 2011
Annual report of the U.S. Climate Change Science Program documenting activities and research, goals for the upcoming year, proposed budget considerations, and other information about the organization for fiscal year ...
Climate Change Science Program (U.S.)
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

U.S. National Climate Change Assessment

, 2014
The report summarizes the science of climate change and the impacts of climate change in the United States, now and in the ...
Yohe, Gary W., Terese Richmond, U.S. Global Change Research Program, Melillo, Jerry M.   +3 more
core  

Public Health Perspectives on Motivation and Behavior Change in Physical Activity

, 2019
This chapter addresses behavior change for physical activity, mainly from a public health perspective. We briefly cover established concepts, theories and frameworks before outlining some important contemporary approaches, identifying knowledge gaps, and
Biddle, Stuart J. H., Vergeer, Ineke
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The National Global Change Research Plan 2012-2021: A Triennial Update

, 2017
This report is the third triennial update of the National Global Change Research Plan based on scientific research from 13 Federal agencies. The purpose of each update is to "advance science, inform decisions, conduct...assessments" and communicate ...
U.S. Global Change Research Program
core  

User-centered design and development of a web-based tool to support healthy feeding practices by parents of urban minority youth at risk for childhood obesity

Digital Health
Objectives Technology, mobile health (mHealth), and “eHealth” are broadly used in childhood overweight and obesity interventions. However, the impact of technology-based interventions where parents or caregivers are involved is unclear.
Katrina F Mateo, Helene Vilme, Sandra Verdaguer, Abigail Fuqua, Kris Hoyt, Jacquelyn Davis, May May Leung   +6 more
doaj   +1 more source