Results 111 to 120 of about 10,938,470 (249)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Behavior Change in Use of Transport to Reduce CO2 Emissions
Mobility is very important for individuals in each group of age. European Union has put a goal for sustainable mobility, thinking not only about effective transport modes but also about impact on environment as and human health. As part of European Union,
Savicka, Elīna +2 more
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Beyond success stories: learning from behavioral interventions in zoo conservation fundraising
Frontiers in Conservation ScienceBackgroundEfforts to stem the species extinction crisis have been hampered by lack of funding. While public investment is key, private donations play an important role in wildlife conservation.ObjectiveThis study investigated whether persuasion ...
Joao Neves +3 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Behaviour Change Research and Theory: Psychological and Technological Perspectives.
, 2016 This volume provides a unified account of behavior change theories and broad coverage of application domains and best practices. From a psychological and human-computer interaction perspective, the book puts a strong emphasis on the psychological ...
Little, Linda +2 more
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Promising behavior change techniques for climate-friendly behavior change – a systematic review
Frontiers in Public HealthIntroductionBesides societal and governmental actions to mitigate greenhouse gases, individual behavioral changes are also urgently needed to limit global temperature rise.
Lisa Masciangelo +6 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 2008 This is an excerpt of a report series produced by the U.S. Climate Change Science Program (CCSP) aimed at providing current assessments of climate change science to inform public debate, policy, and operational decisions.
Subcommittee on Global Change Research +1 more
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, 2022 Gabriela Schmid-Mohler,1,2 Christine Hübsch,1,2 Claudia Steurer-Stey,3,4 Nico Greco,5 Macé M Schuurmans,2,6 Sonja Beckmann,1 Paul Chadwick7 *, Christian Clarenbach2,6 𪇎ntre of Clinical Nursing Science, University Hospital Zurich, Zurich ...
Clarenbach C +7 more
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