Results 131 to 140 of about 11,021,950 (406)

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1422-1435, May 2025.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina   +17 more
wiley   +1 more source

Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1155-1169, April 2025.
We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park   +8 more
wiley   +1 more source

A Curious Case of Flower Phobia: Anthophobia

open access: yesAnnals of the National Academy of Medical Sciences (India), 2017
Fears, anxieties and specific phobias are classified as internalizing behavior problems. The development of specific phobias may result from the pairing of a specific object or situation with the emotion of fear.
Desiree Saimbi   +4 more
doaj   +1 more source

What do Families and Teams Have in Common?

open access: yes, 2014
They both have built-in support groups, and they’re both subjects of interest to Brad Donohue. The UNLV psychology professor takes the principles of Family Behavior Therapy and applies them in a variety of contexts, including athletic ...
Lien, Scott
core  

When Group Spirit Meets Personal Journeys: Exploring Motivational Dynamics and Design Opportunities in Group Therapy [PDF]

open access: yesarXiv
Psychotherapy, such as cognitive-behavioral therapy (CBT), is effective in treating various mental disorders. Technology-facilitated mental health therapy improves client engagement through methods like digitization or gamification. However, these innovations largely cater to individual therapy, ignoring the potential of group therapy-a treatment for ...
arxiv  

Different Strategies for Cancer Treatment: Mathematical Modeling [PDF]

open access: yesarXiv, 2006
We formulate and analyze a mathematical model describing immune response to avascular tumor under the influence of immunotherapy and chemotherapy and their combinations as well as vaccine treatments. The effect of vaccine therapy is considered as a parametric perturbation of the model.
arxiv  

Internet-Based Cognitive Behavior Therapy for Loneliness: A Pilot Randomized Controlled Trial.

open access: yesThe Behavior Therapist, 2020
Anton Käll   +7 more
semanticscholar   +1 more source

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