Results 131 to 140 of about 1,419,032 (336)

PENERAPAN COGNITIVE BEHAVIOR THERAPY (CBT) PADA KLIEN SKIZOFRENIA DENGAN MASALAH KEPERAWATAN ISOLASI SOSIAL : MENARIK DIRI DI RUMAH SAKIT JIWA MENUR SURABAYA [PDF]

open access: yes, 2016
Isolasi sosial merupakan suatu keadaan perubahan yang dialami klien skizofrenia. Suatu satu keluhan yang diderita menyendiri dari seseorang dan perasaan segan terhadap orang lain sebagai sesuatu yang negatif.
SITTA, NUSRATUS
core  

Cognitive-Behavioral Therapy

open access: yes, 2012
Cognitive-behavioral therapy (CBT) encompasses various psychotherapeutic approaches that are rooted in the fundamental principle that a person’s thinking is the prime determinant of emotional and behavioral responses to life situations. The historical influences of CBT can be found in the behavioral approaches: John Watson’s classical conditioning and ...
A. Antonio González-Prendes   +3 more
openaire   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Treatment Outcomes for At-Risk Young Children With Behavior Problems: Toward a New Definition of Success [PDF]

open access: yes, 2014
This study examined the outcomes of Early Pathways (EP), an in-home parent–child therapy program with 447 at-risk children younger than 5 years of age who were referred for severe behavior and emotional problems, such as aggression, oppositional behavior,
Fox, Robert A.   +2 more
core   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Effective Interventions for Treating Superficial Self Mutilators [PDF]

open access: yes, 2008
Self-cutting is the most common form of self-mutilation in adolescents but there is insufficient knowledge as to which treatment methods to reduce self-mutilation are most effective.
Palladini, Maria
core   +1 more source

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