Results 71 to 80 of about 11,348,603 (380)

Serial amplification of tau filaments using Alzheimer's brain homogenates and C322A or C322S recombinant tau

open access: yesFEBS Letters, EarlyView.
We investigated the seeded assembly of 0N3R tau and two variants, C322A and C322S, designed to model the mutation landscape at residue 322, using Alzheimer's disease brain homogenates in a real‐time quaking‐induced conversion (RT‐QuIC) assay. The C322A variant formed filaments that partially resembled the paired helical filament (PHF) structure ...
Alessia Santambrogio   +9 more
wiley   +1 more source

Hürthle cell carcinoma: current perspectives. [PDF]

open access: yes, 2016
Hürthle cell carcinoma (HCC) can present either as a minimally invasive or as a widely invasive tumor. HCC generally has a more aggressive clinical behavior compared with the other differentiated thyroid cancers, and it is associated with a higher rate ...
Ahmadi, Sara   +3 more
core   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Pre-therapy process and outcome: A review of research instruments and findings [PDF]

open access: yes, 2008
Pre-Therapy aims at stimulating psychological contact in persons suffering psychosis. We offer a review of Pre-Therapy research instruments and findings.
Dekeyser, Mathias   +2 more
core  

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Latino Acculturative Stress Implications, Psychotherapeutic Processes, and Group Therapy [PDF]

open access: yes, 2012
The Latino population is the fastest growing ethnic minority group in the United States. Yet, Latinos do not receive adequate mental health treatment due to the lack of cultural sensitivity regarding the necessity of bilingual and bicultural staff and ...
Doucette, David W, Russell, Micah
core   +1 more source

Murine and human myogenic cells identified by elevated aldehyde dehydrogenase activity: Implications for muscle regeneration and repair [PDF]

open access: yes, 2011
Background: Despite the initial promise of myoblast transfer therapy to restore dystrophin in Duchenne muscular dystrophy patients, clinical efficacy has been limited, primarily by poor cell survival post-transplantation. Murine muscle derived stem cells
Bucsek, MJ   +4 more
core   +4 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Expected Practice as a Novel Antibiotic Stewardship Intervention. [PDF]

open access: yes, 2019
"Expected practice" is a recently described method to alter clinical behavior. We implemented an expected practice around short-course antibiotic therapy, which was associated with decreased antibiotic utilization for multiple bacterial infections. Thus,
Masuda, Eriko   +3 more
core  

Efektivitas "Cognitive Behavior Therapy" Terhadap Penurunan Derajat Stres [PDF]

open access: yes, 2013
Cognitive Behavior Therapy (CBT) is an effective way to decrease the degree of stress in patients with chronic Low Back Pain (LBP). Chronic LBP can be divided to physical and psychogenical view.
Setianto, L. (Luki), Yusuf, U. (Umar)
core   +2 more sources

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